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ChemicalBook Product Catalog Namodenoson

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Namodenoson NEW

$72.00 5mg

$122.00 10mg

$247.00 25mg

Min. Order
Purity99.40%
Cas No163042-96-4
Supply Ability10g
Update time2026-04-12

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

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Chemical Properties

Product Name	Namodenoson
CAS No	163042-96-4
EC-No
Min. Order
Purity	99.40%
Supply Ability	10g
Release date	2026/04/12

Product Introduction

Bioactivity

Name	Namodenoson
Description	Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.
Animal Research	Rats were randomly assigned to two treatment groups of 6 animals, which received either two subsequent intravenous infusions of 200 μg/kg 2-chloro-N^6-(3-iodobenzyl)adenosine-5′-N-methylcarboxamide (2-Cl-IB-MECA) during 15 min or two subsequent infusions of the vehicle during 15 min. 2-Cl-IB-MECA was dissolved in dimethylsulfoxide (DMSO) and diluted with a sodium chloride solution to a final 30% (v/v) DMSO solution (a total volume of 765 μl).?Fresh solutions were prepared prior to each experiment.The effect measurements were started at least 45 min prior to the first drug infusion and lasted until 4.5 h after this infusion.?Heart rate and blood pressure were recorded continuously and serial arterial blood samples were drawn for determination of plasma histamine concentrations.?2 h after the first administration the second dose of 2-Cl-IB-MECA (or vehicle) was administered[1].
In vivo	The first infusion of Namodenoson resulted in a rapid fall of the blood pressure to a value which was about 50% of the pre-administration level.The hypotension was short-lasting.After approximately 15 min the blood pressure started to recover and rapidly returned to stable values, which were significantly lower than the blood pressure values in the control group.Administration of the second dose of Namodenoson, at 150 min after the first infusion, did not produce any hypotension at all.The slight increase in the mean arterial pressure during the second infusion was not specific for Namodenoson[1]
Storage	Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 31 mg/mL (56.91 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.67 mM), Sonication is recommended.
Keywords	P1 receptor \| Namodenoson \| Inhibitor \| inhibit \| CF102 \| CF 102 \| AdenosineReceptor \| Adenosine Receptor \| A3
Inhibitors Related	Xanthine \| Theophylline monohydrate \| Diphylline \| Adenosine monophosphate \| Acefylline \| Sulcatone \| Adenosine 5'-monophosphate monohydrate \| Inosine \| Theobromine \| Adenosine 5'-monophosphate disodium salt \| Theophylline \| Doxofylline
Related Compound Libraries	Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| ReFRAME Related Library \| Anti-Obesity Compound Library \| Anti-Cancer Clinical Compound Library \| Drug Repurposing Compound Library \| Bioactive Compounds Library Max \| Covalent Inhibitor Library \| GPCR Compound Library \| Human Metabolite Library \| Anti-Cancer Active Compound Library \| Anti-Cancer Drug Library

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