| Name | Naringin |
| Description | Naringin (Naringoside), a flavanone glycoside, exerts various of pharmacological effects such as blood lipid lowering, antioxidant activity, anticancer activity, and inhibition of cytochrome P450 enzymes. |
| Cell Research | HBZY-1 cells are plated into 96-well plates and pretreated with various concentrations(1, 5, 10, 25, 50, 100 μM) of naringin for 2 h. Then cells are treated with 30 mM glucose for 24 h. The control group is added sterile normal saline in the same volume. After treatment, all the wells are incubated with 20 μL of 5 mg/ml MTT for 4 h at 37°C. Subsequently, 100 μL of DMSO are used to dissolve the formed formazan crystals after removal of the supernatant. The result is recorded at 490 nm on a microplate reader[1]. |
| In vivo | The Lethal Dose 50 for mice:1650 mg/kg. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 1 mg/mL (1.72 mM), Sonication is recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 250 mg/mL (430.64 mM), Sonication is recommended.
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| Keywords | Naringin | Mitophagy | Mitochondrial Autophagy | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | Cytochrome P450 | CYPs | CYP450 | Autophagy |
| Inhibitors Related | Sucrose | Aceglutamide | Hemin | Nicotinamide riboside malate | DL-Lysine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium |
| Related Compound Libraries | Polyphenolic Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Miao medicine Compound Library | Saccharide and Glycoside Natural Product Library | Natural Product Library | Natural Product Library for HTS | Bitter Compound library | Cosmetic Ingredient Compound Library | Flavor Natural Product library | Bioactive Compounds Library Max |
United States
