| NADP disodium (24292-60-2) |
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| NADP disodium, also known as β-Nicotinamide adenine dinucleotide phosphate disodium salt. β-Nicotinamide adenine dinucleotide phosphate, a coenzyme composed of ribosylnicotinamide 5′-phosphate (NMN) coupled by pyrophosphate linkage to the 5′-phosphate adenosine 2′,5′-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). |
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| Name | NADP Disodium salt |
| CAS | 24292-60-2 |
| Purity | 98% |
| Chemical name | β-Nicotinamide adenine dinucleotide phosphate disodium salt |
| Synonyms | β-NADH phosphate disodium salt, Triphosphopyridine nucleotide disodium salt, β-NADP-Na2, β-Nicotinamide adenine dinucleotide phosphate disodium salt |
| Molecular Formula | C21H26N7Na2O17P3 |
| Molecular Weight | 787.37g/mol |
| InChI Key | WSDDJLMGYRLUKR-WUEGHLCSSA-L |
| Form | Solid |
| Appearance | White powder |
| Solubility | Soluble in water (100 g/l) at 20° C. |
| Application | IVD ，Enzymatic synthesis |
| Testing Document | Available |
| Storage Condition | Keep dry ,away from light, and store at 2℃- 8℃, long term store at -15℃ to -25℃ |
| Package | 10gram/bag ,50gram/bag , 1KG/bag, 25KG/drum |
| EC Index Number: | 246-129-8 |
| λmax | 260 nm |
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| DESCRIPTION |
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| General description |
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| Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. |
| Application |
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| The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay. |
| Preparation Note |
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| Storage conditions (working solution): 2 to 8 °C |
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| 10 mg/ml in aqueous solution, contains at least 99% NADP after 4 weeks at 2 to 8 °C |
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| Analysis Note |
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| Absorbance coefficients: 18.0 x 103 [l x mol-1 x cm-1] at 260 nm, 5.9 x 103 [l x mol-1 x cm-1] at 333 nm (CN complex) |
| Absorbance at 340 nm: Imidazol buffer, 100 mM pH 6.7, NADP 2 mM (= 14.87 mg/10 ml) : A340 approximately 0.100. |
| Absorbance at 360 nm: Aqueous solution of NADP, 10 mg/ml: A360 approximately 0.200-0.250. |
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