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Nicotinic acid NEW
- Min. Order1KG
- Purity99%
- Cas No59-67-6
- Supply Abilityg-kg-tons, free sample is available
- Update time2025-09-25
China
| Product Name | Nicotinic acid |
| CAS No | 59-67-6 |
| EC-No | |
| Min. Order | 1KG |
| Purity | 99% |
| Supply Ability | g-kg-tons, free sample is available |
| Release date | 2025/09/25 |
1. Materials information
Names
| Name | Nicotinic acid |
|---|---|
| Synonym | More Synonyms |
Nicotinic acid Biological Activity
| Description | Niacin (Vitamin B3) is a water-soluble vitamin and is part of the vitamin B group.Target: OthersNiacin (also known as vitamin B3 and nicotinic acid) is an organic compound with the formula C6H5NO2 and, depending on the definition used, one of the 20 to 80 essential human nutrients. Not enough niacin in the diet can cause nausea, skin and mouth lesions, anemia, headaches, and tiredness. Chronic Niacin deficiency leads to a disease called pellagra. The lack of niacin may also be observed in pandemic deficiency disease which is caused by a lack of five crucial vitamins: niacin,vitamin C, thiamin, vitamin D and vitamin A, and is usually found in areas of widespread poverty and malnutrition.Niacin has been used for over 50 years to increase levels of HDL in the blood and has been found to decrease the risk of cardiovascular events modestly in a number of controlled human trials. Niacin cannot be directly converted to nicotinamide, but both compounds could be converted to and are precursors of NAD and NADP in vivo.Nicotinic acid, nicotinamide, and tryptophan (via quinoline acid) are co-factors for nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). NAD converts to NADP by phosphorylation in the presence of the enzyme NAD+ kinase. NADP and NAD are coenzyme for many dehydrogenases, participating in many hydrogen transfer processes. NAD is important in catabolism of fat, carbohydrate, protein, and alcohol, as well as cell signaling and DNA repair, and NADP mostly in anabolism reactions such as fatty acid and cholesterol synthesis.High energy requirements (brain) or high turnover rate (gut, skin) organs are usually the most susceptible to their deficiency. |
|---|---|
| Related Catalog | Signaling Pathways >> Autophagy >> Autophagy Natural Products >> Others Research Areas >> Metabolic Disease |
| Target | Human Endogenous Metabolite |
| References | [1]. Bruckert E, et al. Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis. Atherosclerosis. 2010 Jun;210(2):353-61. [2]. Wan P, et al. Pellagra: a review with emphasis on photosensitivity. Br J Dermatol. 2011 Jun;164(6):1188-200. [3]. Ishii N, et al. Pellagra among chronic alcoholics: clinical and pathological study of 20 necropsy cases. J Neurol Neurosurg Psychiatry. 1981 Mar;44(3):209-15. |
Chemical & Physical Properties
| Density | 1.473 |
|---|---|
| Boiling Point | 292.5±13.0 °C at 760 mmHg |
| Melting Point | 234-238 ºC |
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 |
| Flash Point | 130.7±19.8 °C |
| PSA | 55.98000 |
| LogP | 0.15 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.571 |
| Storage condition | 0-6°C |
| Stability | Stable. Incompatible with strong oxidizing agents. May be light sensitive. |
| Water Solubility | 1-5 g/100 mL at 17 ºC |
MSDS
Nicotinic acid MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Safety Information
| Symbol |  GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | 2810.0 |
| WGK Germany | 1 |
| RTECS | QS3675000 |
| Hazard Class | 6.1 |
| HS Code | 29362990 |
Synthetic Route
Previous 1/75 Next Nicotinyl alcoh... 100-55-0 ~95%  Nicotinic acid 59-67-6 |
| Literature: Mirza-Aghayan, Maryam; Molaee Tavana, Mahdieh; Boukherroub, Rabah Tetrahedron Letters, 2014 , vol. 55, # 2 p. 342 - 345 |
 3-Mepy 108-99-6 ~99% Nicotinic acid 59-67-6 |
| Literature: Jubilant Life Sciences Limited Patent: EP2428505 A2, 2012 ; Location in patent: Page/Page column 6-7 ; |
 Nicotinic acid ... 2398-81-4 ~85% Nicotinic acid 59-67-6 |
| Literature: Ryzhakov, A. V.; Elaev, N. R. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 8 p. 859 - 861 Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 8 p. 1075 - 1076 |
Precursor & DownStream
| Precursor 9 | Previous 1/3 Next |
|---|---|
| |
| DownStream 10 | Previous 1/3 Next |
| |
CAS#:500-22-1
CAS#:10354-56-0
CAS#:109822-09-5
CAS#:5006-66-6
CAS#:609-71-2Customs
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Tina@fdachem.com
Mob: 86 15225627621
WhatsApp/Skype/Wechat/LINE: 86 15225627621
Company Profile Introduction
Henan Fengda Chemical Co., Ltd. a research customization and supplier specializing in PPb grade ultra-high purity electronic chemicals, deeply rooted in the semiconductor and new display fields, committed to providing the most core and purest chemical components for photoresist and high-end display materials. We provide key monomers for KrF/ArF photoresist, photoacid generators (PAGs), photoacids, and etching solution raw materials, providing cornerstone materials for advanced process photoresist formulations; We take ICP-MS full spectrum metal impurity analysis as the quality cornerstone and provide ICP-MS metal impurity COA reports to meet the strict industry requirements for PPb grade electronic chemical materials. The COA report contains important data such as NA, Mg, K, Ca, Al, Cr, Fe, Ni, Cu, Zn, Pb, Ag, etc. To provide customers with pure and reliable source assurance for cutting-edge research and stable production.
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