NNMTi 5-amino-1MQ NEW

CAS number

42464-96-0

EINECS number

464-196-0

Synonym

NNMTi; 5-amino-1MQ; 5-Amino-1-methylquinolinium iodide; 5-Amino-1methylquinolinium iodide;5-Amino-1-methylquinolinium; 1-methylquinolin-1-ium-5-amine iodide

Description

5-Amino-1-methylquinolinium iodide, also known as 5-Amino-1MQ iodide, is a quinolinium derivative. It is a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which plays a crucial role in NAD+ metabolism . This compound has been studied for its potential therapeutic applications, particularly in cancer treatment and metabolic health.
It has been used in various scientific studies to target NNMT, leading to significant reductions in tumor growth and enhanced apoptotic effects in cancer models . Additionally, it has shown promise in promoting fat loss, enhancing energy expenditure, and improving metabolic health, making it a promising candidate for obesity treatment and age-related metabolic support