| Name | Oleuropein |
| Description | Oleuropein is an antioxidant polyphenol isolated from olive leaf. |
| In vitro | In both J774A.1 cells and primary mouse macrophages, Oleuropein increases LPS-induced NO production. [1] Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion. [2] In TF-1a; 786-O, T-47D, RPMI-7951, LoVo, and NL-Fib cells, Oleuropein inhibits cell proliferation and migration. [3] |
| In vivo | In swiss albino mice that spontaneously develop soft tissue sarcomas, Oleuropein (i.p. or p.o.) completely regresses tumors. [3] In rats, Oleuropein (40 mg/kg, p.o.) protects from cardiac remodeling process after isoproterenol-induced myocardial infarction through inhibiting angiotensin-converting enzyme activity. [4] |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.7 mM), Sonication is recommended.
DMSO : 50 mg/mL (92.51 mM), Sonication is recommended.
H2O : 92 mg/mL (170.21 mM), Sonication is recommended.
Ethanol : 93 mg/mL (172.06 mM), Sonication is recommended.
|
| Keywords | ROS | PPARγ | PPAR | Peroxisome proliferator-activated receptors | olive | Oleuropein | oil | leaves | Inhibitor | inhibit | cancer | breast | Aromatase | Apoptosis | antioxidant | anti-inflammatory | anti-atherogenic |
| Inhibitors Related | Ethoxyquin | Kaolin | Stavudine | Aceglutamide | Allopurinol | Urea | Daidzein | Metronidazole | Ethyl linoleate | Formamide | Naringin | Alginic acid |
| Related Compound Libraries | Polyphenolic Natural Product Library | Terpene Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Natural Product Library for HTS | Bitter Compound library | Flavor Natural Product library | Anti-Aging Compound Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-Cancer Active Compound Library |
United States
