| Name | Oxybutynin chloride |
| Description | Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. |
| In vitro | Oxybutynin relieves urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder. Oxybutynin competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. [1] Oxybutynin also has direct spasmolytic effects on bladder smooth muscle as a calcium antagonist and local anesthetic, but at concentrations far above those used clinically. [2] |
| Storage | 02 | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 73 mg/mL (185.3 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.08 mM), Sonication is recommended.
DMSO : 55 mg/mL (139.61 mM), Sonication is recommended.
H2O : 4 mg/mL (10.15 mM), Sonication is recommended.
|
| Keywords | urinary urgency | urinary incontinence | urinary frequency | PotassiumChannel | Potassium Channel | Oxybutynin Hydrochloride | Oxybutynin chloride | Oxybutynin | OAB | Muscarinic acetylcholine receptor | mAChR | Kv channels | KcsA | Inhibitor | inhibit |
| Inhibitors Related | Adiphenine hydrochloride | Urethane | Hexamethonium Bromide | 1,8-Cineole | Tetraethylammonium bromide | Adenine | Ursodeoxycholic acid | Mitotane | Chenodeoxycholic acid | N,N-Dicyclohexylcarbodiimide | Arecoline | Chlorzoxazone |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
United States
