| Name | Pancreatic Polypeptide, rat acetate |
| Description | Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4. |
| In vitro | Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic Polypeptide, rat acetate (1 μM) does not alter proliferation in BRIN BD11 or 1.1B4 beta-cells, but reverses the decreased cell viability in BRIN BD11 cells induced by streptozotocin. Pancreatic Polypeptide, rat acetate (0.1 nM-1 μM) shows no effect on insulin secretion from isolated mouse islets, and does not affect the membrane potential and (Ca2+)i levels in BRIN BD11 cells at 1 μM[1]. |
| In vivo | Pancreatic Polypeptide, rat acetate (25 nmol/kg bw, i.p.) reduces glucose-stimulated insulin concentrations but shows no effect on acute feeding behaviour in overnight fasted mice[1]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 252.5 mg/mL, Sonication is recommended.
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| Keywords | Pancreatic Polypeptide, rat acetate | NeuropeptideYReceptor | Neuropeptide Y Receptor | neuropeptide Y (NPY) receptor |
| Inhibitors Related | [Leu31,Pro34]-Neuropeptide Y (porcine) | Lu AA33810 | (S)-VU0637120 | Galanin (1-16), mouse, porcine, rat | SF 11 | GW438014A | M617 acetate | JNJ-31020028 | Galantide acetate | DF-1012 FA | M871 acetate | Pancreatic Polypeptide (human) acetate |
| Related Compound Libraries | Peptide Compound Library |