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ChemicalBook Product Catalog API Circulatory system drugs Antiarrhythmics Drugs Propafenone

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Propafenone NEW

$39.00 25mg

$64.00 50mg

$105.00 100mg

Min. Order
Purity99.69%
Cas No54063-53-5
Supply Ability10g
Update time2025-05-01

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP2Y

United States

United States

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Chemical Properties

Product Name	Propafenone
CAS No	54063-53-5
EC-No
Min. Order
Purity	99.69%
Supply Ability	10g
Release date	2025/05/01

Product Introduction

Bioactivity

Name	Propafenone
Description	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated. The electrophysiological effect of propafenone manifests itself in a reduction of upstroke velocity (Phase 0) of the monophasic action potential. In Purkinje fibers, and to a lesser extent myocardial fibers, propafenone reduces the fast inward current carried by sodium ions, which is responsible for the drugs antiarrhythmic actions. Diastolic excitability threshold is increased and effective refractory period prolonged. Propafenone reduces spontaneous automaticity and depresses triggered activity. At very high concentrations in vitro, propafenone can inhibit the slow inward current carried by calcium but this calcium antagonist effect probably does not contribute to antiarrhythmic efficacy.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 25 mg/mL (73.22 mM), Sonication is recommended.
Keywords	sodium-channel blocker \| SodiumChannel \| Sodium Channel \| SA-79 \| SA79 \| SA 79 \| Propafenone \| PotassiumChannel \| Potassium Channel \| Na+ channels \| Na channels \| MRP1 \| mitochondrial dysfunction \| mitochondria dysfunction \| KcsA \| Ito \| Isus \| Inhibitor \| inhibit \| esophageal \| ESCC \| Drug repositioning \| Beta Receptor \| apoptosis \| antiarrhythmic agent \| Adrenergic Receptor
Inhibitors Related	Minoxidil sulfate \| Phenytoin sodium \| Procaine \| Tannic acid \| Lidocaine \| Hydrochlorothiazide \| Valproic Acid \| Lidocaine hydrochloride \| L-Aspartic aicd sodium \| Ursodeoxycholic acid \| Cholesterol \| Indapamide
Related Compound Libraries	Pain-Related Compound Library \| Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| Drug Repurposing Compound Library \| Inhibitor Library \| Neuroprotective Compound Library \| Anti-Cancer Approved Drug Library \| FDA-Approved Drug Library \| Immunology/Inflammation Compound Library \| Bioactive Compounds Library Max \| Ion Channel Targeted Library \| Anti-Cancer Drug Library

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