Remdesivir (CAS 1809249-37-3)
🌟 ChemicalBook Product Introduction
📌 Product Overview
Remdesivir (GS-5734) is a broad-spectrum antiviral nucleotide analog with the molecular formula C27H35N6O8P. As a prodrug of GS-441524, it inhibits RNA-dependent RNA polymerase (RdRp), effectively blocking viral replication by incorporating into viral RNA chains. Primarily used to treat COVID-19, it also demonstrates activity against Ebola, MERS-CoV, and SARS-CoV. Supplied as a white crystalline powder with ≥99% purity (HPLC verified), it is stable under recommended storage conditions (-20°C).
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✅ Key Advantages
🔹 High Purity & Stability
≥99% purity (HPLC/UV verified) | Long-term stability at -20°C.
🔹 Potent Antiviral Activity
EC50 = 30 nM against murine hepatitis virus (MHV) | 74 nM EC50 for SARS-CoV and MERS-CoV in HAE cells.
🔹 Global Compliance
Produced in GMP-certified facilities | Complies with EP/USP/CP standards.
🏥 Application Fields
COVID-19 Treatment: Approved for emergency use in severe cases.
Ebola & MERS Research: Clinical trials for filovirus infections.
Antiviral Development: Key component in RNA virus therapeutic research.
📜 Quality Certifications
Testing Methods: HPLC, NMR, MS, and microbial limit testing.
Certifications: ISO 9001, GMP, and FDA-aligned protocols.
📊 Market Trends
The global antiviral drug market is projected to grow at 6.5% CAGR (2025-2030), driven by persistent COVID-19 variants and emerging RNA virus threats. Remdesivir remains a frontline therapeutic, with Asia-Pacific regions leading production and R&D.
China
