| Name | Riboflavin |
| Description | Riboflavin (Vitamin B2) is a natural product, an endogenous human metabolite, and a micronutrient. Riboflavin is essential for the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. Riboflavin is involved in energy metabolism, cellular respiration, and antibody production, as well as normal growth and development. |
| In vitro | METHODS: Rat pancreatic islet cells were treated with Riboflavin (10 µM) for 3 days and cell viability was measured by Trypan blue assay.
RESULTS: Riboflavin supplementation had no effect on the viability of HEK293T17 cells. [1]
METHODS: Rainbow trout gonadal cells RTG-2 were treated with Riboflavin (10 µM) for 24 h. Islet number was measured by DTZ staining.
RESULTS: Riboflavin-treated islets had modest but statistically significantly higher recovery rates of 75.2±1.6% and 69.3±2.0%, respectively. [2] |
| In vivo | METHODS: To investigate the effects on LPS-induced shock in mice, Riboflavin (1-10 mg/kg) was injected intraperitoneally into BALB/c mice, followed by LPS.
RESULTS: High doses of Riboflavin reduced LPS-induced mortality by increasing HSP25 expression. [3] |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 3.76 mg/mL (10 mM), Sonication is recommended.
H2O : Insoluble
|
| Keywords | Vitamin B-2 | Vitamin B 2 | VB2 | Riboflavin | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | E-101 | E 101 |
| Inhibitors Related | Sucrose | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Drug Repurposing Compound Library | Tobacco Monomer Library | Cosmetic Ingredient Compound Library | Bitter Compound library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Gut Microbial Metabolite Library | Ancient Chinese Classical Formulas Compound Library |
United States
