Rutin trihydrate with CAS 250249 - 75 - 3 is a natural flavonoid glycoside with diverse biological activities. It has a wide range of applications in the pharmaceutical and healthcare, cosmetics, food, and chemical analysis fields. The specific applications are as follows:
Pharmaceutical and healthcare field
Supporting cardiovascular health: It is often added to dietary supplements because it can strengthen blood vessels and improve blood circulation. Moreover, its antioxidant properties can reduce oxidative damage to cardiovascular cells, and it also has a certain protective effect on the heart, which is of great significance for maintaining cardiovascular health.
Alleviating diabetes - related complications: It can reduce the level of reactive oxygen species, thereby reducing oxidative stress on neurons and helping to control neuropathy (including auditory neuropathy) in diabetic patients. This makes it a potential auxiliary substance for the adjuvant treatment of diabetes - related complications.
Anti - inflammatory and relieving inflammatory diseases: It can inhibit the production of pro - inflammatory cytokines such as tumor necrosis factor - alpha and interleukin - 6 to exert anti - inflammatory effects. It is used in some formulations to alleviate inflammatory disorders such as arthritis.
Neuroprotective research and application: It can cross the blood - brain barrier and improve the viability of nerve cells. For example, in vitro experiments have shown that it can significantly reduce the cytotoxicity induced by acrylamide in PC12 cells. In addition, it can also improve the cognitive and behavioral symptoms of neurodegenerative diseases, providing a research basis and potential application direction for the treatment of neurodegenerative diseases.
Cosmetics field
It is widely used in skin care products due to its excellent antioxidant properties. It can resist oxidative stress on the skin, reduce skin damage caused by ultraviolet rays, delay skin aging, and help maintain healthy skin state.
Food field
It serves as a natural food additive. On one hand, its antioxidant properties can slow down the oxidation and deterioration of food and extend the shelf life of food; on the other hand, as a natural flavonoid, it can increase the nutritional value of food and is added to various processed foods to enhance their nutritional content.
Chemical analysis field
It can be used to make electrochemical sensors. Researchers have prepared a redox - active modified electrode by immobilizing rutin trihydrate on a multi - walled carbon nanotube composite material. This electrode has high selectivity and sensitivity to the toxic and carcinogenic substance hydrazine. It can be used for hydrazine detection in real samples such as tanker water, tap water, and wastewater, with a low detection limit and good recovery rate.
Laboratory research field
It is a common research reagent. It is used in in - vitro and in - vivo pharmacological experiments, such as studying the mechanism of action of flavonoid compounds on cells and animals, or exploring the pathological mechanisms of diseases such as inflammation and neurodegeneration. Additionally, it is also applied in the Japanese Pharmacopoeia's crude drug thin - layer chromatography identification tests, playing a role in the qualitative analysis of crude drugs.
China
