Rutinose Cas 90-74-4
Product Description
Product Name: Rutinose
Synonyms: 6-o-(alpha-L-Rhamnosyl)-D-glucose
CAS No. 90-74-4
M.F.: C12H22O10
M.W.: 326.3
EINECS: 202-014-4
Specifications
Items | Specifications | Results |
Appearance | A white or off-white power | Complies |
Solubility | Easily soluble in water. Clear and colorless solution | Complies |
MS and NMR | Should comply | Complies |
Water | Max. 10% | 4.42% |
Assay by HPLC based on ELSD | Min. 95% | 98.5% |
Conclusion | The product conforms to the above specifications. |
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Rutinose is a naturally occurring disaccharide—a sugar composed of two linked monosaccharide units. Specifically, it consists of α-L-rhamnose joined by an α(1→6) glycosidic bond to D-glucose. Unlike common dietary sugars, rutinose is not typically found in its free form in nature. Instead, it serves a critical role as the glycosidic side chain attached to certain flavonoid molecules, profoundly influencing their properties and functions.
Chemical Structure and Significance
The unique combination of rhamnose and glucose in this specific linkage makes rutinose a key determinant of the solubility, stability, and biological activity of the compounds it forms. The rhamnose unit, in particular, contributes to the molecule's hydrophilicity and interaction with enzymes and receptors.
Primary Role: The Sugar Moiety in Important Bioactive Flavonoids
Rutinose's major importance lies in its role as part of several prominent flavonoid glycosides, which are widespread in plants and significant for human health:
Rutin (Quercetin-3-O-rutinoside): This is the most famous compound containing rutinose. Rutin is a powerful antioxidant and vasoprotective agent found in foods like buckwheat, asparagus, and citrus fruits. The rutinose sugar group is essential for rutin's bioavailability and its ability to strengthen capillaries.
Hesperidin (Hesperetin-7-O-rutinoside): A major flavonoid in citrus peels, hesperidin contributes to vascular health and has anti-inflammatory effects. The rutinose moiety influences its absorption and metabolism.
Naringin (Naringenin-7-O-rutinoside): Found abundantly in grapefruit, naringin is responsible for its characteristic bitter taste. The rutinose unit is cleaved off in the gut to produce the aglycone naringenin.
Functional Impact of the Rutinose Group
Solubilization: Attaching the hydrophilic rutinose disaccharide to a fat-soluble flavonoid aglycone (like quercetin) dramatically increases its water solubility, allowing for better distribution in plant tissues and in the human bloodstream.
Bioavailability & Metabolism: The rutinose linkage affects how the flavonoid is absorbed and metabolized. In the human intestine, specific gut bacteria produce enzymes (α-rhamnosidases) that can cleave the rutinose unit, releasing the active aglycone for absorption or further transformation.
Biological Activity: The presence and specific structure of the rutinose sugar can enhance or modify the antioxidant, anti-inflammatory, and cellular signaling activities of the parent flavonoid compared to its unsweetened form.
Potential Applications and Research
While not used directly as an ingredient, rutinose is relevant in:
Nutraceutical and Pharmaceutical Research: Understanding its role in flavonoid metabolism helps optimize the formulation of herbal extracts (like rutin or hesperidin supplements) for improved efficacy.
Synthetic Biology and Enzymology: The enzymes that synthesize or break down the rutinose bond (rhamnosyltransferases and rhamnosidases) are targets for research, potentially enabling the commercial production of high-value flavonoids.
Food Science: Its presence influences the taste profile (e.g., bitterness of naringin) and nutritional value of plant-based foods.
In summary, rutinose is far more than just a simple sugar. It is a crucial functional module in nature's design of important bioactive flavonoids, governing their behavior in both plants and the humans who consume them. Its study sits at the intersection of carbohydrate chemistry, phytochemistry, and nutritional pharmacology.
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Different products have different MOQ, such as:
1).Peptide products, the MOQ is 1 gram level
2).Liquid products, the MOQ is usually 50-100ML
3).API, the MOQ is 1KG
4).Intermediate products and conventional product, the MOQ is 1KG; custom-tailored products, the MOQ depends on the production process.
5).Food additives and vitamin, the MOQ is usually one package: such as Vitamin C is 25KG / drum, Vitamin E oil or Vitamin A oil is 5KG/bag;Vitamin E powder or Vitamin A powder is 20KG / cartons.
6).Agrochemical , the MOQ is 1KG, except preparations.
6.How do we take the quality complaint ?
First of all, our quality control will reduce the quality issue to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or compensate your loss.
Company Information
Company profile
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.
We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.
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