| Name | Sennoside A |
| Description | Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. |
| In vitro | Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine through regulating the spontaneous motility of colon. [2] It mildly inhibits bovine serum monoamine oxidase with IC50 of 17 μM. [1] |
| In vivo | LD50: Mice 5000 mg/kg (i.g.); Rats 5000 mg/kg (i.g.). [3] |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 135 mg/mL (156.48 mM), Sonication is recommended.
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (3.83 mM), Sonication is recommended.
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| Keywords | Sennoside A | NSC-112929 | NSC112929 | MAO | Inhibitor | inhibit | Human immunodeficiency virus | HIVProtease | HIV Protease | HIV |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Dolutegravir intermediate-1 | Lamivudine | Triphenyl phosphate | 1,4-Naphthoquinone | Valproic Acid | Paeonol | (-)-Epigallocatechin Gallate | Decanedioic acid | Dextran sulfate sodium salt (MW 5000) |
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