PRODUCT INFORMATION
Names
| Name | silychristin |
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| Synonym | More Synonyms |
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Silicristin Biological Activity
| Description | Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2]. |
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| Related Catalog | Research Areas >> Endocrinology Signaling Pathways >> Others >> Others |
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| References | [1]. Biedermann D, et al. Silychristin: Skeletal Alterations and Biological Activities. J Nat Prod. 2016 Dec 23;79(12):3086-3092. [2]. Johannes J, et al. Silychristin, a Flavonolignan Derived From the Milk Thistle, Is a Potent Inhibitor of the Thyroid Hormone Transporter MCT8. Endocrinology. 2016 Apr;157(4):1694-701. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 782.0±60.0 °C at 760 mmHg |
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| Molecular Formula | C25H22O10 |
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| Molecular Weight | 482.436 |
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| Flash Point | 270.5±26.4 °C |
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| Exact Mass | 482.121307 |
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| PSA | 166.14000 |
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| LogP | 2.20 |
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| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
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| Index of Refraction | 1.716 |
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| Storage condition | 2-8°C |
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Safety Information
| Symbol | 
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Hazard Codes | Xn |
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| Risk Phrases | 22 |
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| Safety Phrases | 22-45 |
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| RIDADR | NONH for all modes of transport |
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Precursor & DownStream
| Precursor 3 |
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 CAS#:1835-11-6
1-(4-(Benzyloxy...
 CAS#:124662-51-7
1-(4-benzyloxy-...
 CAS#:16414-34-9
Benzaldehyde,3-...
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Company Profile
Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.
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