Sodium gentisate Cas 4955-90-2
Specification
Items | Specifications | Results |
Appearance | A white or almost red crystalline powder | Pass |
Water | No more than 18.0% | 15.8% |
Purity | ≥99.0% | 99.7% |
Conclusion | The product conforms to the above specifications. |
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Sodium Gentisate is the sodium salt of gentisic acid (2,5-dihydroxybenzoic acid). It appears as a white to off-white crystalline powder and is highly soluble in water.
Key Properties & Background
Origin: Gentisic acid is a primary metabolite of acetylsalicylic acid (aspirin) in the human body.
Key Traits: It retains some anti-inflammatory and analgesic properties of its parent compound but is often valued for its antioxidant and chelating abilities.
Primary Uses
1. Pharmaceutical & Medical
Analgesic & Anti-inflammatory Agent: Used as an active ingredient in some analgesic and anti-arthritic formulations, particularly in certain European and Asian markets. It is sometimes promoted as a better-tolerated alternative for individuals sensitive to aspirin.
Stabilizer & Antioxidant in Formulations: Acts as an antioxidant preservative in injectable solutions and other pharmaceutical preparations.
2. Veterinary Medicine
Large Animal Analgesic: Its most significant and common use is in veterinary medicine, especially for horses, cattle, and dogs. It is administered via intravenous or intramuscular injection to treat musculoskeletal pain, inflammation, and fever.
3. Research & Biochemical Applications
Analytical Reagent: Used in laboratory colorimetric tests and assays.
Precursor in Organic Synthesis: Serves as a starting material or intermediate for synthesizing more complex organic compounds, including potential drugs and dyes.
Model Compound: Studied for its metabolic pathways and antioxidant mechanisms.
4. Cosmetic & Skincare
Why the Sodium Salt?
The sodium salt form (sodium gentisate) is used instead of the free acid (gentisic acid) primarily for two practical reasons:
Enhanced Solubility: It is much more soluble in water, facilitating the preparation of stable injectable solutions and liquid formulations.
Improved Bioavailability: The salt form generally allows for better and faster absorption in the body.
In summary, Sodium Gentisate is a versatile metabolite of aspirin used chiefly as a veterinary analgesic and anti-inflammatory drug, with additional roles as a pharmaceutical excipient, research chemical, and cosmetic antioxidant.
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