| Name | SRPIN340 |
| Description | SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM). |
| In vitro | In Flp-In293 cells, SRPIN340 inhibited SR phosphorylation via SRPK, promoted SRp75 degradation, and subsequently inhibited the production of HIV.In CHO cells, SRPIN340 (5 mg/ml) did not produce abnormalities in chromosome structure and chromosome number. |
| In vivo | In Flp-In293 cells, SRPIN340 inhibited SR phosphorylation via SRPK, promoted SRp75 degradation, and subsequently inhibited the production of HIV.In CHO cells, SRPIN340 (5 mg/ml) did not produce abnormalities in chromosome structure and chromosome number. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : 65 mg/mL (186.06 mM), Sonication is recommended. DMSO : 250 mg/mL (715.61 mM), Sonication is recommended. 10% DMSO+90% Saline : 2.5 mg/mL (7.16 mM), Sonication is recommended.
|
| Keywords | VirusProtease | Virus Protease | threoninkinase | threonin kinase | SRPK1 | SRPK | SRPIN-340 | SRPIN340 | SRPIN 340 | Serinekinase | Serine-arginine protein kinases | Serine kinase | Inhibitor | inhibit |
| Inhibitors Related | Rifampicin | Phenytoin sodium | Levofloxacin hydrochloride | Ribavirin | Anthraquinone | L-Lysine | L-Lysine hydrochloride | Ofloxacin | Vidarabine | Thymidine | N4-Acetylcytidine | Danthron |
| Related Compound Libraries | Highly Selective Inhibitor Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Viral Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Cell Cycle Compound Library | Anti-Cancer Compound Library |