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ChemicalBook Product Catalog Biochemical Engineering Plant extracts Plant Extracts Strophanthidin

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Strophanthidin NEW

$ 42.00 /5mg

Min. Order
Purity94.68%
Cas No66-28-4
Supply Ability10g
Update time2026-04-14

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP6Y

United States

United States

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Chemical Properties

Product Name	Strophanthidin
CAS No	66-28-4
EC-No
Min. Order
Purity	94.68%
Supply Ability	10g
Release date	2026/04/14

Product Introduction

Bioactivity

Name	Strophanthidin
Description	Strophanthidin (Strophanthidine) can induce calcium overload in vivo.
In vitro	The effect of potassium and rubidium on the electrical and mechanical activity of canine Purkinje fibers were studied in vitro in the presence and absence of strophanthidin. METHODS AND RESULTS: High (5.4mM) K or 2.7 Rb decreased the force of contraction. In the presence of these ions, strophanthidin(Strophanthidine) increased the force of contraction as usual but the onset of arrhythmias was delayed. During the toxic stage of strophanthidin, high K or Rb increased the force of contraction, abolished the arrhythias and improved markedly the action potential. In the presence of calcium overload induced by exposure to a K-poor or Na-free solution, K and Rb induced an increase in force of contraction. And in ventricular muscle these ions relaxed the contracture induced by strophanthidin. CONCLUSIONS: It is concluded that K and Rb (in addition to other mechanisms) exert an antiarrhythmic action by increasing potassium conductance and by reducing the calcium overload induced by strophanthidin.
Storage	Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 25.00 mg/mL (61.80 mM), Sonication is recommended.
Keywords	systolic \| Strophanthidin \| Sodium potassium pump \| sarcolemmal \| naturally \| Na+/K+ ATPase \| Inhibitor \| inhibit \| glycoside \| diastolic \| cardiac \| CalciumChannel \| Calcium Channel \| available
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