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ChemicalBook Product Catalog Chemical pesticides Herbicide Urea herbicides Sulfometuron-methyl

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Sulfometuron-methyl NEW

$50.00 5mg

$72.00 10mg

$129.00 25mg

Min. Order
Purity99.77%
Cas No74222-97-2
Supply Ability10g
Update time2026-04-13

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP6Y

United States

United States

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Chemical Properties

Product Name	Sulfometuron-methyl
CAS No	74222-97-2
EC-No
Min. Order
Purity	99.77%
Supply Ability	10g
Release date	2026/04/13

Product Introduction

Bioactivity

Name	Sulfometuron-methyl
Description	Sulfometuron-methyl (DXP-5648) is a herbicide and also is an active antibacterial agent. It is an effective inhibitor of acetolactate synthase II and thus shows antibacterial properties.
In vitro	The sulfonylurea herbicide sulfometuron methyl inhibits the growth of several bacterial species. In the presence of L-valine, sulfometuron methyl inhibits Salmonella typhimurium, this inhibition can be reversed by L-isoleucine. Reversal of growth retardation by L-isoleucine, accumulation of guanosine 5'-diphosphate 3'-diphosphate (magic spot), and relA mutant hypersensitivity suggest sulfometuron methyl interference with branched-chain amino acid biosynthesis. Growth inhibition of S. typhimurium is mediated by sulfometuron methyl's inhibition of acetolactate synthase, the first common enzyme in the branched-chain amino acid biosynthetic pathway. Sulfometuron methyl exhibits slow-binding inhibition of acetolactate synthase isozyme II from S. typhimurium with an initial Ki of 660 +/- 60 nM and a final, steady-state Ki of 65 +/- 25 nM. Inhibition of acetolactate synthase by sulfometuron methyl is substantially more rapid (10 times) in the presence of pyruvate with a maximal first-order rate constant for conversion from initial to final steady-state inhibition of 0.25 +/- 0.07 min-1 (minimal half-time of 2.8 min). Mutants of S. typhimurium able to grow in the presence of sulfometuron methyl were obtained. They have acetolactate synthase activity that is insensitive to sulfometuron methyl because of mutations in or near ilvG, the structural gene for acetolactate synthase isozyme II[2].
Storage	Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 18.33 mg/mL (50.3 mM), Sonication is recommended.
Keywords	Sulfometuron-methyl \| Sulfometuronmethyl \| Sulfometuron methyl \| antibacterial
Inhibitors Related	Neomycin sulfate \| Calcium Propionate \| Levulinic acid \| D(+)-Raffinose pentahydrate \| Benzyl propionate \| Sulfamethoxazole sodium \| Terbinafine hydrochloride \| Doxycycline \| Hyaluronic acid sodium (MW 20 kDa) \| Dimethyl sulfoxide \| Sodium diacetate \| Sodium bicarbonate
Related Compound Libraries	Pesticide Compound Library \| Bioactive Compound Library \| Anti-Fungal Compound Library \| Inhibitor Library \| NO PAINS Compound Library \| Anti-Bacterial Compound Library \| Bioactive Compounds Library Max \| Anti-Infection Compound Library \| Human Metabolite Library

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