| Name | Surfactin |
| Description | Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects. |
| In vitro | Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. surfactin can increase the activity of amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC). |
| In vivo | in the model of chick infection, surfactin exerted adjuvant effects with amoxicillin against APEC by lowering the numerical value of mortality and liver bacterial loads, and regulating the expression of inflammatory cytokines et al.We concluded that surfactin can act as a novel antimicrobial adjuvant with amoxicillin against AEPC infection in chicken. |
| Storage | Keep away from moisture |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 2 mg/mL (1.93 mM), Sonication is recommended. H2O : 28.25 mg/mL (27.26 mM), Sonication is recommended. DMSO : 257.5 mg/mL (248.47 mM), Sonication is recommended.
|
| Keywords | Surfactin | HSV-1 |
| Inhibitors Related | Levamisole hydrochloride | Inosine pranobex | Adipic acid | L-Lysine | 2-Deoxy-D-glucose | Oxyresveratrol | Vidarabine | N-Lauroylsarcosine | Acyclovir sodium | Acyclovir | Cytarabine | Trigonelline chloride |
| Related Compound Libraries | Target-Focused Phenotypic Screening Library | Macrocyclic Compound Library | Cyclic Peptide Library | Bioactive Compound Library | Anti-Fungal Compound Library | Anti-Viral Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library | Human Metabolite Library |