TB500, short for Thymosin Beta-4, is a synthetic peptide analog of the endogenous protein thymosin beta-4, which is naturally present in nearly all mammalian cells. Its molecular formula is C212H350N56O78S, with a molar mass of 4963.44 and CAS number 77591-33-4. It is a 43-amino-acid peptide that plays a key role in tissue repair and wound healing.
In scientific research, TB500 has been extensively studied for its biological activities. Preclinical in vitro studies have shown that TB500 (15-25 μg/ml) can promote cell migration and wound healing by enhancing ATP-induced intracellular calcium ion increase and activating purinergic P2 receptors. In vivo experiments on BALB/c mouse skin wound models have demonstrated that topical administration of TB500 (15 μg/30 μl, once daily for 10 days) significantly accelerates wound healing. Additionally, it has been found to be used as a doping agent in horse and greyhound racing due to its tissue repair properties.
The biological mechanism of TB500 mainly involves inhibiting the AKT signaling pathway and binding to actin, thereby exerting anti-fibrotic and wound-healing effects. It promotes endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration and collagen deposition, while reducing inflammation. Its active ingredient, Ac-Tβ4 17-23, also prevents apoptosis, promotes cell survival and immunomodulatory activity by stimulating T cell proliferation.
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**How do I mix peptide powder?**
Use bac water or AA water. Mix 1mL water with 1mg powder. Stir gently. Do not shake hard.
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**How long does unopened peptide last?**
24 months at room temp. 36 months if kept at 2-8°C.
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**How long does mixed peptide last?**
Use within 7 days. Keep at 2-8°C. Do not freeze and thaw repeatedly.
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**How do you ship peptide products?**
We use DHL, FedEx, or UPS. Door-to-door worldwide.
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**What is the minimum order?**
No MOQ for regular items. 200-500 pcs for special specs. Negotiable if you order 200+.
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**How pure is your peptide?**
≥99.8% purity. Tested by HPLC and GC-MS. Meets USP/EP standards.
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**Do you provide COA?**
Yes. If the quantity exceeds 200 boxes, we will provide the COA for that batch of goods.
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**What if I get bad quality product?**
Full refund or free replacement. We reply within 24 hours.
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**How long does delivery take?**
10-15 days worldwide.In some areas, the package will arrive within 10 days. Free shipping for orders over $1000.
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**What if my package is damaged or lost?**
We reship for free. Send us proof. We fix it within 48 hours.
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**Do bulk buyers get special service?**
Yes. You get a dedicated rep. Priority shipping. Free samples for your next order.
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**What certs does your factory have?**
GMP certified. ISO9001 and ISO22000. Meets FDA and CEP standards.
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**Can you make custom peptides?**
Yes. Custom purity, size, and packaging. Takes 15-20 days.
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**How do I track my batch?**
Batch number is on the label. Check it on our website. Every batch is tested by a third-party lab.
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**Do you give discounts for big orders?**
Yes. Contact us on WhatsApp for custom pricing.
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**What if you send the wrong item?**
We reship correct item immediately. No cost to you. Fixed within 24 hours.
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**Do I need to refrigerate dry peptide?**
Room temp is fine. For long term, use 2-8°C. Keep away from sun and heat.
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**Can I get free samples?**
Yes. 1-2 vials free. You pay shipping only.
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**What payment methods do you accept?**
Crypto (no fee), bank transfer, Western Union, PayPal (fees apply). 50% deposit for custom orders（more than 200boxes）.
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**What if my peptide won't dissolve?**
Add a little DMSO first. Then add water. Shake slowly for 1-2 minutes.
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**How do I get bulk pricing info?**
Message us on WhatsApp. Talk to our sales team.whatsapp:0086-17303315735 ;0086-15373916629
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**Which payment has no fees?**
Crypto. Zero fees for all orders.
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