Terbinafine Hydrochloride

$ 1.00 /1kg

Min. Order1kg
Purity99%
Cas No78628-80-5
Supply Ability10000
Update time2026-04-02

HR Biotechnology Co.,Ltd

VIP3Y

China

Since:2019-11-21

Address:Room E020, 4th Floor (1-3), Building 5, International Enterprise Center, No.1 Guanshan Second Road,

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Chemical Properties

Product Name	Terbinafine Hydrochloride
CAS No	78628-80-5
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	10000
Release date	2026/04/02

Property Description

Chemical Name:Terbinafine Hydrochloride

IUPAC Name:(E)-N-(6,6-Dimethyl-2-hepten-4-yn-1-yl)-N-methyl-1-naphthalenemethanamine hydrochloride

CAS:78628-80-5

Molecular Formula:C<sub>21</sub>H<sub>25</sub>N·HCl

Molecular Weight:327.89 g/mol

Appearance:White to off-white crystalline powder

Melting Point:195-198°C (dec.)

Solubility - Water: Slightly soluble

- Methanol/Ethanol: Freely soluble

- Chloroform: Soluble

Pharmacological Class:Allylamine antifungal

Mechanism of Action:Inhibits squalene epoxidase, blocking ergosterol synthesis in fungal cell membranes.

Indication:Treatment of fungal infections (dermatophytes, onychomycosis).

Approval:Approved in 1996 (oral), 1991 (topical)

Chemical Structure:Naphthalene derivative with a tertiary amine group and unsaturated side chain (alkynyl).

Stability:Stable under normal storage conditions (protect from light and moisture).

Parameter	Specification	Test Method	Result
Appearance	White to off-white crystalline powder	Visual inspection	Complies
Identification	IR spectrum matches reference standard	USP <197> / FTIR	Complies
Assay (HPLC)	98.0% - 102.0% (anhydrous basis)	USP <621> (Reverse-phase HPLC)	99.3%
Related Substances	- Individual impurity ≤ 0.5% - Total impurities ≤ 1.5%	HPLC (USP <621>)	0.8% (Total)
Water Content (KF)	≤ 0.5% w/w	Karl Fischer titration	0.2%
Residual Solvents	- Methanol ≤ 3000 ppm - Acetone ≤ 5000 ppm	GC (USP <467>)	<100 ppm
Heavy Metals	≤ 10 ppm (as Pb)	USP <231> / ICP-MS	<5 ppm
Sulfated Ash	≤ 0.1%	USP <281>	0.05%
pH (1% Solution)	4.5 - 6.0	USP <791>	5.2
Melting Point	195-198°C (with decomposition)	USP <741>	196°C (dec.)
Microbial Limits	- TAMC ≤ 1000 CFU/g - TYMC ≤ 100 CFU/g	USP <61>	Complies
Optical Rotation	+0.5° to +2.5° (c=1 in methanol)	USP <781>	+1.8°

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Company Profile Introduction

Wuhan Hao Rong Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.