Tirzepatide for research NEW

Appearance

White or off-white powder

Solubility

Can be dissolved to 5mg/ml in pure water

Molecular Ion Mass

4813.45±1

Amino Acid Analysis

Ser: 4.0 to 6.0

Gly: 3.2 to 4.8

Asp: 1.6 to 2.4

Glu: 3.2 to 4.8

Thr: 1.6 to 2.4

Ala: 3.2 to 4.8

Pro: 3.2 to 4.8

Lys: 1.6 to 2.4

Tyr: 1.6 to 2.4

Ile: 2.4 to 3.6

Lcu: 1.6 to 2.4

Phe: 1.6 to 2.4

Val: 0.8 to 1.2

Aib: 1.6 to 2.4

AEEA: 1.6 to 2.4

Trp: (Det)

PH(C=5mg/ml)

7.0~9.0

Moisture (K.F)

≤ 8.0%

Sodium Ion

≤ 5.0%

Acid Group Ions(HPLC)

TFA≤ 0.1%

PO4^3-≤ 0.1%

Cl^-≤ 0.1%

HAC≤ 0.1%

Related Substances(HPLC)

Maximum single impurity≤ 1.0%

Total impurities≤ 2.0%

Residual Solvents(GC)

Methylene chloride≤ 600ppm

Acetonitrile≤ 410ppm

Methanol≤ 3000ppm

N, N-dimethylformamide≤ 880ppm

Isopropyl Ether≤ 5000ppm

Triethylamine≤ 320ppm

Tert-butyl Methyl Ether≤ 5000ppm

Bacterial Endotoxins

≤ 10EU/mg

Total Plate Count

≤ 1000cfu/g

Yeasts&Molds

≤ 100cfu/g

E.Coli

Negative

Salmonella

Negative

Pseudomonas Aeruginosa

Negative

Staphylococcus Aureus

Negative

High Molecular Protein

≤ 0.5%

Peptide Content

(Mass Balance)

≥ 80.0%

Purity (HPLC)

≥ 98.0%

Assay (HPLC)

95.0%~105.0%

(on anhydrous and salt-freesubstance basis)