| Name | Triacetylresveratrol |
| Description | Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells. |
| Cell Research | Apoptosis was determined by using apoptosis detection kit according to the manufacturers instructions.?Briefly, cells were treated with the indicated dosage of Acetyl-trans-resveratrol?for 48 h. The untreated and?treated cells were washed with PBS buffer and gently suspended in Annexin V binding buffer and incubated with Annexin V-FITC (20 μg/mL) and PI (20 μg/mL) for 15 minutes in the dark.?Flow cytometry analysis was performed using Cellquest software. |
| In vitro | Acetyl-trans-resveratrol inhibited cell viability, and induced apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1]. |
| In vivo | Acetyl-trans-resveratrol significantly inhibited intracranial tumor growth and prolonged survival in these mouse models[2]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 247.5 mg/mL (698.46 mM), Sonication is recommended.
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| Keywords | Triacetylresveratrol | STAT3 | STAT | Resveratrol | PANC-1 | Nuclear factor-κB | Nuclear factor-kappaB | NF-κB | NFκB | NF-kB | NFkB | Mcl-1 | Inhibitor | inhibit | BxPC-3 | Anticancer |
| Inhibitors Related | Cyanoacetamide | Flubendazole | Sodium propionate | Ethyl palmitate | Kojic acid | Uridine | Fumaric acid | 1,4-Naphthoquinone | Glucosamine | Ethyl linoleate | N,N-Dimethylacetamide | Magnesium sulfate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Natural Product Library | Miao medicine Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-Cancer Active Compound Library |
United States
