Product Name: Trifluoromethanesulfonic Acid (Triflic Acid)
CAS No.: 1493-13-6
Molecular Formula: CF₃SO₃H
Molecular Weight: 150.07 g/mol
Overview:
Trifluoromethanesulfonic acid (TfOH) is one of the strongest known organic acids, classified as a superacid and renowned as a "versatile synthetic tool". It is an extremely strong Brønsted acid with acidity (pKa ≈ -14.7) far exceeding that of 100% sulfuric acid. Its exceptional protonating and catalytic power, combined with the outstanding stability of its conjugate base (triflate ion) (high thermal stability, non-nucleophilic, and inert to oxidation/reduction), enables highly efficient catalysis under demanding conditions. Unlike traditional mineral acids, it avoids side reactions like sulfonation, making it a superior, high-performance alternative for process optimization.
Key Advantages:
High Purity & Stable Supply: Our industrial-scale distillation and purification processes guarantee a consistent product with a main content of ≥98%. The acid exhibits remarkable stability towards strong acids and redox environments, ensuring a long shelf life.
Superior Performance: As a superacid, its catalytic efficiency far surpasses that of conventional mineral acids. It can significantly reduce catalyst loadings while improving yield and selectivity in numerous reactions, optimizing process costs from the outset.
Scalable Production Capacity: With in-house manufacturing facilities and automated production lines, we ensure stable and continuous supply from kilogram to ton scale, securing the supply chain for large-volume clients.
Significant Cost & Service Advantage: Leveraging optimized domestic production and integrated supply chains, we offer more competitive pricing for the local market compared to international suppliers, backed by a local technical support team for rapid response.
Physicochemical Properties:
Appearance: Colorless liquid, fuming in moist air.
Boiling Point: 162 °C (1013 hPa).
Melting Point: -40 °C.
Density: ~1.70 g/cm³ (20°C).
Solubility: Miscible with water with vigorous evolution of heat. Soluble in polar organic solvents (e.g., DMSO, acetonitrile).
Hazards: Severely corrosive (Skin Corr. 1B). Harmful if inhaled or swallowed. Full personal protective equipment is mandatory for handling.
Primary Applications:
Triflic acid serves as a highly efficient catalyst, dehydrating agent, and activator in various fields:
Organic Synthesis & Pharmaceutical Intermediates: Catalyzes esterifications, Friedel-Crafts acylations/alkylations, Diels-Alder cycloadditions, olefin polymerizations, rearrangements, and domino reactions for synthesizing nucleosides, antibiotics, steroids, vitamins, and more.
Polymer Chemistry: Functions as a potent cationic initiator for the polymerization of olefins, epoxides, vinyl ethers, etc., leading to high-performance polymers.
Peptide Synthesis & Protecting Group Chemistry: Used for final global deprotection and cleavage in Boc-based Solid-Phase Peptide Synthesis (SPPS).
Specialty Chemical Synthesis: Key reagent for preparing triflic anhydride, triflate esters (triflates), diaryliodonium salts, and other critical intermediates.
Packaging & Storage:
Packaging: Available in sealed glass or plastic bottles of 100g, 500g, 1kg, etc. Customized packaging is available upon request.
Storage: Must be kept tightly sealed in a cool, dry, and well-ventilated place. Due to its strong hygroscopicity and corrosivity, storage at 2-30°C is recommended.
We welcome inquiries, collaboration, and sample requests from all new and existing customers in pharmaceuticals, agrochemicals, polymer materials, electronic chemicals, and fine chemicals!
Yurui(Shanghai) Chemical Co. Ltd / UIV Chem
Contact Person: Nan Haodong
Address: Floor 5, Building H2, No.3188 Xiupu Rd, Pudong, Shanghai 201203, China
Tel: 0086-21-50456736 / 021-33191321
WhatsApp: +86 17613296318
WeChat: NHDong2021
Email: xin@riyngroup.com
QQ: 2551819264
Website: www.riyngroup.com
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