Product Name:Trilostane
Synonyms:TRILOSTANE;(2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car;17-beta)-ph;(4a,5a,17b)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile;5a-Androstane-2a-carbonitrile, 4a,5-epoxy-17b-hydroxy-3-oxo-;Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4a,5a,17b)-;4α,5-Epoxy-3,17β-dihydroxy-5α-androst-2-ene-2-carbonitrile;4α,5-Epoxy-3,17β-dihydroxy-5α-androstan-2-ene-2-carbonitrile
CAS:13647-35-3
MF:C20H27NO3
MW:329.43
EINECS:237-133-0
Uses:Trilostane has been used to evaluate its capability to regulate the sex-dependent differences in the lipopolysaccharide (LPS)-induced inflammatory responses of astrocytes.

| Specification | Test Method | Result |
|
|---|
| Product Name | Trilostane | Visual/Label Verification | Complies |
| CAS No. | 13647-35-3 | - | 13647-35-3 |
| Molecular Formula | C<sub>20</sub>H<sub>27</sub>NO<sub>3</sub> | - | Complies |
| Appearance | White to off-white crystalline powder | Visual | White powder |
| Identification | IR / HPLC / NMR matches reference | USP/EP | Complies |
| Assay (Purity) | 98.0% - 102.0% | HPLC | 99.5% |
| Melting Point | 120°C - 124°C | USP 741 | 122°C |
| Loss on Drying | ≤ 0.5% | USP 731 | 0.2% |
| Related Substances | Individual impurity ≤ 0.5% | HPLC | 0.3% (Max) |
| Total Impurities | ≤ 2.0% | HPLC | 1.2% |
| Residual Solvents | Complies with ICH Q3C | GC | Complies |
| Heavy Metals | ≤ 20 ppm | USP 231 | <10 ppm |
| Microbial Limits | ≤ 1000 CFU/g (Total Aerobic Count) | USP 61 | Complies |
| Endotoxins | < 0.5 EU/mg (if applicable) | USP 85 | <0.2 EU/mg |
