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Product Overview: Urolithin A Diacetate
CAS Number: 1163-12-8
Chemical Name: [3-acetyloxy-6-oxobenzo[c]chromen-8-yl] acetate
Molecular Weight: 312.27 g/mol
Introduction
Urolithin A Diacetate is a synthetic derivative and a precursor (prodrug) of Urolithin A. Urolithin A itself is a natural metabolite produced by the gut microbiome from ellagitannins and ellagic acid, which are found in fruits like pomegranates, strawberries, and walnuts.
While Urolithin A is famous for its "anti-aging" properties, the diacetate version is often used in research and specialized supplement formulations because the acetylation of the hydroxyl groups can improve the compound's stability and bioavailability (how well it is absorbed by the body) compared to the raw form.
Primary Uses and Functions
1. Mitochondrial Health (Mitophagy)
The most significant use of Urolithin A Diacetate is its ability to stimulate mitophagy. This is the process where the body identifies and "recycles" damaged or aging mitochondria (the powerhouses of the cell). By clearing out dysfunctional mitochondria, it helps cells function more efficiently and stay younger.
2. Anti-Aging and Longevity
In biological research, this compound is studied for its potential to extend lifespan and improve healthspan. By enhancing cellular energy and reducing oxidative stress, it helps combat the natural decline associated with aging.
3. Muscle Function and Recovery
Studies have shown that Urolithin A derivatives can improve muscle strength and endurance, particularly in aging populations or those with muscle-wasting conditions. It helps maintain the integrity of muscle tissue by ensuring the energy-producing units (mitochondria) are healthy.
4. Anti-Inflammatory Properties
It exhibits significant anti-inflammatory effects. It can inhibit various inflammatory pathways, making it a subject of interest for research into chronic inflammatory diseases and metabolic health.
5. Laboratory Research (R&D)
Because of its CAS-specific identity, it is widely sold as a high-purity chemical reagent for:
In vitro studies on cell signaling.
In vivo animal trials to test metabolic improvements.
Development of advanced nutritional supplements.
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