Sex enhancement Vardenafil CAS: 224785-90-4 Factory Directly supply
Generic Name:Vardenafil
CAS Number:224785-90-4
Molecular Formula • Free base: C₂₃H₃₂N₆O₄S
• Hydrochloride trihydrate (common pharmaceutical salt): C₂₃H₃₂N₆O₄S·HCl·3H₂O
Molecular Weight • Free base: 488.6 g/mol
• Hydrochloride trihydrate: 579.1 g/mol
Physical & Chemical Properties
Appearance:White to off-white powder
Melting Point:230-235 °C
Solubility >22.5 mg/mL in DMSO; 7 mg/L in water at 20°C
Acidity Coefficient (pKa):9.86 ± 0.20 (Predicted)
Partition Coefficient (LogP):2.5 at 23°C
Storage Conditions:Sealed in dry, store at -20°C or 2-8°C, protected from light
Pharmacological Profile
Pharmacological Class:Phosphodiesterase type 5 (PDE5) inhibitor
Primary Indication:Treatment of erectile dysfunction (ED)
Mechanism of Action:Potent, selective, and competitive inhibition of the PDE5 enzyme. This increases intracellular levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum and facilitating erection.
Selectivity:Highly selective for PDE5 over other PDE isoforms (e.g., IC₅₀ for PDE1 is 180 nM, for PDE6 is 11 nM).
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Core Strengths | Specific Highlights |
Supply Chain Excellence | • Integrated manufacturing & QC processes • Strategic partnerships with 100+ certified suppliers • MOQ flexibility (from samples to bulk orders) |
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Cost Optimization | • Raw material sourcing from top-tier suppliers • Energy-efficient manufacturing • 5-15% cost advantage vs. competitors |
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