| Name | Vasopressin |
| Description | Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pituitary-adrenal axis, increasing the amount of solute free water reabsorbed from the renal tubule's colate back into the circulation, narrowing arteries to increase pressure, enhancing the stimulating effect of corticotropin releasing factor to regulate pituitary corticotropin secretion. Vasopressin acts as a neurotransmitter during nerve conduction by binding to specific G-protein-coupled receptors. |
| In vitro | AVP (0.01 nM-1 μM) induces Ca2+ elevation in Chinese hamster ovary cells expressing rat or human V1b receptors.[1] |
| In vivo | Vasopressin (0.03-0.3 μg/kg; i.p.) enhances corticotropin release elicited by exogenous corticoliberin and amplifies corticotropin secretion following dehydration.[1]
Vasopressin (0.001-0.1 mg/kg; i.p.) significantly promotes proximity, wherein rats encountering each other for the first time exhibit passive side-by-side positioning.[2] |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (3.04 mM), Sonication is recommended.
DMSO : 90 mg/mL (83.01 mM), Sonication is recommended.
H2O : 45 mg/mL (41.5 mM), Sonication is recommended.
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| Keywords | Vasopressin | Microbial Metabolite | EndogenousMetabolite | Endogenous Metabolite | AVP | arginine vasopressin | antidiuretic hormone | ADH |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | DL-Lysine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium |
| Related Compound Libraries | Macrocyclic Compound Library | Food Sourced Compound Library | Approved Drug Library | Natural Product Library | Natural Product Library for HTS | Human Endogenous Metabolite Compound Library Plus | Human Metabolite Library |
United States
