Basic information Safety Related Supplier

ChemicalBook Product Catalog Biochemical Engineering Biochemical Reagents Agonist Inhibitors Wiskostatin

1/1

Wiskostatin NEW

$38.00 1mg

$89.00 5mg

$128.00 10mg

Min. Order
Purity99.84%
Cas No253449-04-6
Supply Ability10g
Update time2026-04-13

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP6Y

United States

United States

show more

Enterprise Verified

Business Bank account Basic Contact Infomation Business Address Trade Company

Chemical Properties

Product Name	Wiskostatin
CAS No	253449-04-6
EC-No
Min. Order
Purity	99.84%
Supply Ability	10g
Release date	2026/04/13

Product Introduction

Bioactivity

Name	Wiskostatin
Description	Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization.
Kinase Assay	Enzyme kinetic analysis is performed on the purified wild type and mutant UL97 protein species using increasing concentrations of ATP (2 μM to 20 μM). The amount of incorporated radiolabelled phosphate is plotted against the concentration of ATP in a Lineweaver Burke plot to determine the Km for ATP for each UL97 species. The effect of Maribavir upon the rate of radiolabelled phosphate incorporation by wild type or mutant UL97 is determined by protein kinase assays at a fixed concentration of Maribavir (0.5 μM) as above, or with increasing concentrations of Maribavir (0.01 μM to 5.0 μM) to determine the IC50 of Maribavir for each UL97 species. In order to determine the nature of the inhibition mediated by Maribavir, plots of 1/v vs 1/ATP with increasing concentrations of Maribavir are constructed. Competitive inhibition is evident if the family of lines cconverged on the y-axis at 1/Vmax. The change in slope caused by the addition of Maribavir is used to calculate the Ki[1].
Storage	Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 76.9 mg/mL (180.45 mM), Sonication is recommended. 10% DMSO+90% Corn Oil : 2.5 mg/mL (5.87 mM), Sonication is recommended.
Keywords	Wiskostatin \| WASP(Arp)2/3 \| selective \| N-WASP \| neuronal \| irreversible \| Inhibitor \| inhibit \| ATP \| Arp2/3 Complex \| Actin-related protein 2/3 complex \| actin polymerization
Inhibitors Related	PLH1215 \| SMIFH2 \| CK-666 \| Jasplakinolide \| Dihydrocytochalasin B \| CK-869 \| Benproperine phosphate \| NSC305787 hydrochloride \| CK-636 \| Cytochalasin D \| BDP-13176 \| NSC305787
Related Compound Libraries	Bioactive Compound Library \| Inhibitor Library \| NO PAINS Compound Library \| Bioactive Compounds Library Max \| Cytoskeletal Signaling Pathway Compound Library \| Anti-COVID-19 Compound Library

show more

Company Profile Introduction

You may like

Recommended supplier

Send Inquriy