Basic information Description Indications Dose titration Plasma levels monitoring Cautions Interactions Special populations Behavioural and cognitive effects in patients with epilepsy Psychiatric use References Safety Related Supplier

ChemicalBook Product Catalog API Nervous system drugs Antiepileptic and anticonvulsant Zonisamide

1/1

Zonisamide NEW

$40.00 50mg

$59.00 100mg

$79.00 200mg

Min. Order
Purity99.76%
Cas No68291-97-4
Supply Ability10g
Update time2025-04-27

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP2Y

United States

United States

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Chemical Properties

Product Name	Zonisamide
CAS No	68291-97-4
EC-No
Min. Order
Purity	99.76%
Supply Ability	10g
Release date	2025/04/27

Product Introduction

Bioactivity

Name	Zonisamide
Description	Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels results in a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may lower the uptake of the inhibitory neurotransmitter GABA while increasing the uptake of the excitatory neurotransmitter glutamate.
In vitro	Zonisamide inhibits monoamine oxidase B activity in vitro with an IC50 of 25 μM.
In vivo	Zonisamide inhibits monoamine oxidase B activity in vitro with an IC50 of 25 μM.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 55 mg/mL (259.15 mM), Sonication is recommended.
Keywords	Zonisamide \| SodiumChannel \| Sodium Channel \| SH-SY5Y \| seizure \| parkinson's disease \| NRCMs \| Inhibitor \| inhibit \| epilepsy \| CI-912 \| CI912 \| cardiac hypertrophy \| cardiac fibroblasts \| CarbonicAnhydrase \| Carbonic anhydrase \| Carbonic Anhydrase \| Carbonate dehydratase \| CalciumChannel \| Calcium Channel \| Apoptosis \| AD-810 \| AD810
Inhibitors Related	Benzenesulfonamide \| Phenytoin sodium \| Procaine \| Cyclamic acid sodium \| L-Ascorbic acid \| Valproic Acid \| L-Phenylalanine \| Lidocaine hydrochloride \| L-Aspartic aicd sodium \| Ethyl cinnamate \| L-Ascorbic acid sodium salt \| 2-Nitrobenzoic acid
Related Compound Libraries	Failed Clinical Trials Compound Library \| Pain-Related Compound Library \| Bioactive Compound Library \| Anti-Neurodegenerative Disease Compound Library \| Membrane Protein-targeted Compound Library \| Anti-Cancer Clinical Compound Library \| Drug Repurposing Compound Library \| Neuroprotective Compound Library \| FDA-Approved Drug Library \| Bioactive Compounds Library Max \| Ion Channel Targeted Library \| Anti-Cancer Drug Library

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