长沙上禾生物新橙皮苷 (Neohesperidin) 中英文简介

产品名称

新橙皮苷

Neohesperidin (Neohesperidin Dihydrochalcone Precursor)

植物来源

芸香科植物酸橙 (Citrus aurantiumL.) 的果皮、幼果，以及枳 (Poncirus trifoliata) 等柑橘属植物。

Peel and unripe fruit of Citrus aurantiumL. (Rutaceae), and other citrus species like Poncirus trifoliata.

化学分类

二氢查耳酮苷 (Dihydrochalcone Glycoside)，一种柑橘类黄酮。

Dihydrochalcone Glycoside, a type of Citrus Flavonoid.

外观性状

白色至类白色结晶性粉末，味先微苦后极甜。

White to off-white crystalline powder, taste is slightly bitter first, then intensely sweet.

核心化学信息

化学名称： (S)-7-[[2-O-(6-脱氧-α-L-甘露吡喃糖基)-β-D-葡萄糖吡喃氧基]]-5-羟基-2-(3-羟基-4-甲氧基苯基)-4-氧代-4H-1-苯并吡喃

Chemical Name: (S)-7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-1-benzopyran

CAS No.

13241-33-3

13241-33-3

分子式

C₂₈H₃₄O₁₅

C₂₈H₃₄O₁₅

分子量

610.56 g/mol

610.56 g/mol

主要规格

高纯度标准品：Neohesperidin ≥98%, ≥95% (HPLC)
食品/原料级：Neohesperidin ≥90%, ≥80% (HPLC/UV)
橙皮苷/新橙皮苷复合物：按客户需求定制比例

High Purity Standard: Neohesperidin ≥98%, ≥95% (HPLC)
Food/Raw Material Grade: Neohesperidin ≥90%, ≥80% (HPLC/UV)
Hesperidin/Neohesperidin Complex: Customized ratios per client requirements

检测方法

HPLC, UV

HPLC, UV

溶解度

微溶于水，溶于稀碱液、热甲醇、热乙醇、DMSO。

Slightly soluble in water, soluble in dilute alkaline solution, hot methanol, hot ethanol, DMSO.

药理与功能功效

1. 天然高效甜味剂前体 (Natural High-Intensity Sweetener Precursor)：核心功能。经氢化可生成新橙皮苷二氢查耳酮 (Neohesperidin Dihydrochalcone, NHDC)，其甜度是蔗糖的1500-1800倍，口感清爽，无苦后味，是高倍天然甜味剂的核心原料。
2. 抗氧化与抗炎 (Antioxidant & Anti-inflammatory)：清除自由基，抑制脂质过氧化，抑制炎症因子（如TNF-α, IL-6, COX-2），保护细胞。
3. 调节糖脂代谢 (Regulates Glucose & Lipid Metabolism)：改善胰岛素抵抗，降低血糖和血脂水平，对糖尿病和肥胖症有潜在益处。
4. 心血管保护 (Cardioprotective)：改善血管内皮功能，降低血管通透性和脆性，辅助降血压。
5. 神经保护 (Neuroprotective)：可能通过抗氧化和抗炎途径，对神经退行性疾病有保护作用。
6. 抑菌 (Antibacterial)：对部分革兰氏阳性菌和阴性菌有抑制作用。

1. Natural High-Intensity Sweetener Precursor: Core function. Hydrogenation yields Neohesperidin Dihydrochalcone (NHDC), which is 1500-1800 times sweeter than sucrose with a clean, refreshing taste and no bitter aftertaste. It is a key raw material for high-intensity natural sweeteners.
2. Antioxidant & Anti-inflammatory: Scavenges free radicals, inhibits lipid peroxidation, suppresses inflammatory factors (e.g., TNF-α, IL-6, COX-2), and protects cells.
3. Regulates Glucose & Lipid Metabolism: Improves insulin resistance, lowers blood glucose and lipid levels, offering potential benefits for diabetes and obesity.
4. Cardioprotective: Improves vascular endothelial function, reduces vascular permeability and fragility, and aids in lowering blood pressure.
5. Neuroprotective: May protect against neurodegenerative diseases through antioxidant and anti-inflammatory pathways.
6. Antibacterial: Inhibits certain Gram-positive and Gram-negative bacteria.

应用领域

食品工业：作为新橙皮苷二氢查耳酮 (NHDC) 的核心原料，用于生产高倍天然甜味剂，应用于饮料、糖果、口香糖、酸奶、焙烤食品等，替代阿斯巴甜、糖精等人工甜味剂。
保健品/功能性食品：血糖调节、体重管理、抗氧化、心血管健康类产品的核心功效成分。
医药：作为辅助降糖、降脂、抗炎的原料药或药用辅料（矫味剂）进行研究与应用。
化妆品：抗衰老、抗氧化、抗炎舒缓类护肤品的活性成分。

Food Industry: As the key raw material for Neohesperidin Dihydrochalcone (NHDC), used in producing high-intensity natural sweeteners for beverages, candies, chewing gum, yogurt, baked goods, etc., to replace artificial sweeteners like aspartame and saccharin.
Health Products/Functional Food: Core functional ingredient for blood sugar regulation, weight management, antioxidant, and cardiovascular health products.
Pharmaceuticals: Used as an active pharmaceutical ingredient or excipient (flavor modifier) for auxiliary hypoglycemic, lipid-lowering, and anti-inflammatory purposes in research and applications.
Cosmetics: Active ingredient in anti-aging, antioxidant, and anti-inflammatory soothing skincare products.

法规与安全

中国卫生部公告（2017年第8号）批准柑橘黄酮（以橙皮苷、新橙皮苷等计）为食品营养强化剂和新食品原料。NHDC被中国、美国、欧盟、日本等多国批准为食品添加剂（甜味剂）。GRAS status in USA (GRN No. 677)。

Approved in China as a food nutrient fortifier and new food ingredient (Citrus Flavonoids, calculated as hesperidin, neohesperidin, etc.). NHDC is approved as a food additive (sweetener) in China, USA, EU, Japan, and others. Holds GRAS status in the USA (GRN No. 677).

包装储存

内衬双层聚乙烯袋，外用铝箔袋或纸板桶（1kg/袋，5kg/袋，25kg/桶）。
密封，避光，干燥阴凉处（2-8°C低温保存更佳），保质期2年。

Double-layer polyethylene bag inside, aluminum foil bag or cardboard drum outside (1kg/bag, 5kg/bag, 25kg/drum).
Sealed, stored in a cool, dry place away from light (2-8°C recommended for extended stability). Shelf life 2 years.