普健生物（武汉）科技有限公司

链接：https://www.abinscience.cn/product/78/55017.html

名称：Recombinant FMDV (SAT-1) VP4 Protein, N-His

Accession号：A0A7L4XQ62

货号：VK164032

种属：Foot-and-mouth disease virus SAT 1

表达系统：E. coli

状态：Lyophilized

纯度：>90% as determined by SDS-PAGE.

蛋白长度：Gly200-Ala284

应用：ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

预测分子量：37.01 kDa

用途范围：仅用于科研

储存：Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

产品介绍：近期，我国首次发生输入性南非1型（SAT1）口蹄疫疫情，该血清型为非洲特有毒株，与我国长期流行的 O 型、A 型、亚洲 1 型等毒株在基因组、衣壳结构、抗原蛋白组成及表位构象上存在本质区别，不同血清型间无交叉免疫保护，现有常规疫苗无法提供有效保护。

Recombinant FMDV (SAT-1) VP4 Protein, N-His是武汉艾必赛生物科技有限公司推出的一款高纯度、高活性的重组蛋白。该蛋白靶向口蹄疫病毒（SAT-1型）的VP4衣壳蛋白，是病毒颗粒结构的关键组分，在病毒组装、稳定性和感染过程中扮演重要角色。本品采用大肠杆菌（E. coli） 表达系统制备，带有N端His标签，便于纯化与检测，经SDS-PAGE验证纯度超过90%，预测分子量约为37.01 kDa。该蛋白已严格验证适用于酶联免疫吸附试验（ELISA）、免疫原制备、SDS-PAGE、Western Blot等多种前沿实验技术。其重组表达形式保证了蛋白的一致性与批间稳定性，是研究口蹄疫病毒结构、致病机制、疫苗开发及诊断试剂研制的理想工具试剂。

产品购买联系方式：027-87433958/17302791434

邮箱：info@abinscience.com

参考文献：

Development of two rapid lateral flow test strips for detection of foot-and-mouth disease virus SAT 1 and SAT 3. PMID: 32898572

Unrecognized circulation of SAT 1 foot-and-mouth disease virus in cattle herds around Queen Elizabeth National Park in Uganda. PMID: 26739166

Development of vaccines toward the global control and eradication of foot-and-mouth disease. PMID: 21434805

Development of reverse-transcriptase, real-time PCR assays to distinguish the Southern African Territories (SAT) serotypes 1 and 3 and topotype VII of SAT2 of Foot-and-Mouth Disease Virus. PMID: 36204292

Phylogenomics and molecular evolution of foot-and-mouth disease virus. PMID: 21448588

Genome Sequences of Four Foot-and-Mouth Disease Virus SAT 1 Topotype X Isolates from Cameroon. PMID: 31806747

Seroprevalence of foot-and-mouth disease virus in cattle herds raised in Maasai Mara ecosystem in Kenya. PMID: 32105863

Spatial pattern of foot-and-mouth disease virus serotypes in North Central Nigeria. PMID: 28507418

Foot-and-mouth disease virus serotype SAT1 in cattle, Nigeria. PMID: 28224715

The role of African buffalos (Syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda. PMID: 21143994

Differentiation of the seven serotypes of foot-and-mouth disease virus by reverse transcriptase polymerase chain reaction. PMID: 9274816

Simple and rapid lateral-flow assay for the detection of foot-and-mouth disease virus. PMID: 19726619

Characterisation of recent foot-and-mouth disease viruses from African buffalo (Syncerus caffer) and cattle in Kenya is consistent with independent virus populations. PMID: 25644407

First confirmation of foot and mouth disease virus serotype SAT-1 in cattle and small ruminants in Ethiopia in 2007/08. PMID: 23250672

Foot-and-mouth disease virus detection on a handheld real-time polymerase chain reaction platform. PMID: 31077564

Meta-analysis of genetic diversity of VP1 gene of foot and mouth disease virus serotypes prevalent in Bangladesh from 2010 to 2024. PMID: 41043698

Study on seroprevalence and serotyping of foot and mouth disease in Chad. PMID: 30964458

Characterization of foot-and-mouth disease viruses (FMDVs) from Ugandan cattle outbreaks during 2012-2013: evidence for circulation of multiple serotypes. PMID: 25664876

Serological and phylogenetic characterization of foot and mouth disease viruses from Uganda during cross-sectional surveillance study in cattle between 2014 and 2017. PMID: 31127983

Efficacy of a foot-and-mouth disease vaccine against a heterologous SAT1 virus challenge in goats. PMID: 32312581

Temporal and Spatial Patterns and a Space-Time Cluster Analysis of Foot-and-Mouth Disease Outbreaks in Ethiopia from 2010 to 2019. PMID: 35891538

Molecular Characterization of Foot-and-Mouth Disease Viruses Collected in Tanzania Between 1967 and 2009. PMID: 24460931

Within-Host Viral Growth and Immune Response Rates Predict Foot-and-Mouth Disease Virus Transmission Dynamics for African Buffalo. PMID: 39008835

Evaluation of the solid phase competition ELISA for detecting antibodies against the six foot-and-mouth disease virus non-O serotypes. PMID: 22561986

Differential Persistence of Foot-and-Mouth Disease Virus in African Buffalo Is Related to Virus Virulence. PMID: 26962214

Mutation pressure shapes codon usage in the GC-Rich genome of foot-and-mouth disease virus. PMID: 17768673

Effective Diagnosis of Foot-And-Mouth Disease Virus (FMDV) Serotypes O and A Based on Optical and Electrochemical Dual-Modal Detection. PMID: 34198783

A Simplified mAb-Based Antigen Detection Assay for Rapid Serotyping of Foot-and-Mouth Disease Virus. PMID: 40573352

Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus. PMID: 27168976

Serological profile of foot-and-mouth disease in wildlife populations of West and Central Africa with special reference to Syncerus caffer subspecies. PMID: 26156024

Genetic heterogeneity in the foot-and-mouth disease virus Leader and 3C proteinases. PMID: 12036580

Foot-and-mouth disease virus serotypes detected in Tanzania from 2003 to 2010: conjectured status and future prospects. PMID: 23327382

Investigation of foot-and-mouth disease outbreaks in the Mbala and Kazungula districts of Zambia. PMID: 25134173

Antibodies against foot-and-mouth disease (FMD) virus in African buffalos (Syncerus caffer) in selected National Parks in Uganda (2001-2003). PMID: 20561289

Analysis of synonymous codon usage in foot-and-mouth disease virus. PMID: 20425142

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武汉艾必赛生物技术有限公司成立于 2023 年，是 abinScience 在亚洲地区设立的官方全资子公司，全面负责 abinScience 品牌在亚太市场的科研试剂推广、销售及技术支持工作。

依托严格的产品研发体系和国际化的质量管理标准，武汉艾必赛与 AtaGenix、ProteoGenix 等知名品牌保持长期战略合作，现已构建起涵盖抗体、重组蛋白、工具酶、试剂盒、实验耗材在内的多品类供应体系，面向区域内科研机构、高校实验室与生物医药企业，提供稳定、高效、可信赖的产品与服务。

核心业务覆盖：
✅ 抗体产品（单抗、多抗、重组抗体等）
✅ 蛋白与多肽试剂（标签蛋白、功能蛋白等）
✅ 分子与细胞实验相关耗材
✅ 定制化研发服务（蛋白表达、抗体定制、亲和力成熟等）
✅ 科研供应链整合与项目配套支持

武汉艾必赛始终秉持“Empowering Bioscience Discovery”的理念，为亚太地区的生命科学研究持续注入高质量动能。