IRDye 800CW RGD Optical Probe 光学探头

IRDye 800CW RGD Optical Probe

IRDye 800CW RGD 光学探头

IRDye 800CW RGD 光学探头是一种 BrightSite™ 近红外 (NIR) 荧光标记的 RGD 显像剂，专门设计用于靶向上整合素的过度表达。

整联蛋白是细胞表面异二聚体糖蛋白，参与细胞与细胞和细胞与基质的相互作用。 IRDye 800CW RGD 光学探针由识别基序 RGD (Arg-Gly-Asp) 组成，这是一个三肽序列，用于结合包括 αvβ3 在内的整联蛋白受体。 

IRDye 800CW RGD Optical Probe is a BrightSite™ near-infrared (NIR) fluorescently-labeled RGD imaging agent specifically designed to target the overexpression of integrins on tumors.

Integrins are cell surface heterodimeric glycoproteins involved in cell-to-cell and cell-to-matrix interactions. IRDye 800CW RGD Optical Probe is composed of the recognition motif, RGD (Arg-Gly-Asp), a tripeptide sequence used to bind integrin receptors including αvβ3. This receptor class is involved in tumor growth, tumor invasiveness, metastasis, tumor induced angiogenesis, inflammation, osteoporosis, and rheumatoid arthritis.