aladdin 阿拉丁 M102400 多球壳菌素 35891-70-4 98%

中文名：多球壳菌素

英文名：Myriocin

应用：An inhibitor of sphingolipid biosynthesis with immunosuppressive properties.

纯度：Moligand™，≥98%

货号：M102400

Cas号：35891-70-4

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus (HCV) in a murine model.An inhibitor of sphingolipid biosynthesis with immunosuppressive properties.

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