黄芪甲苷|T6395|TargetMol

Astragaloside
17429-69-5

￥108 5mg 起订

￥140 10mg 起订

询价 25mg 起订

上海更新日期：2026-02-25

TargetMol中国（陶术生物）

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联系人：邵小姐

电话：021-021-33632979拨打

手机：15002134094 拨打

邮箱：marketing@targetmol.com

产品详情:

中文名称：: 黄芪甲苷

英文名称：: Astragaloside

CAS号：: 17429-69-5

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

纯度规格：: 99.90%

产品类别：: 抑制剂

货号：: T4082

Product Introduction

Bioactivity

名称	Astragaloside
描述	Astragaloside, one of the main active ingredients in Astragalus membranaceus.
细胞实验	Cell viability is determined by CCK-8 assay. To be brief, cultured NSCLC cells are seeded into 96-well plates at the density of 4×104 (cells/well). Then 10 μL?well CCK8 solution is added and incubated in dark at 37°C for another 2 h. The absorbance is determined with the wavelength of 490 nm.
激酶实验	Briefly, MDA-MB-231 cells treated as indicated or tumor tissues are harvested and lysed in Mg2+ lysis buffer containing 50 mM Tris (pH 7.5), 10 mM MgCl2, 0.5 M NaCl, and protease inhibitor cocktail. Equal amounts of lysates are incubated with PAK-PBD beads at 4°C for 1 h. PAK-PBD beads are pelleted by centrifugation and washed with ish buffer containing 25 mM Tris (pH 7.5), 30 mM MgCl2, 40 mM NaCl. Active Rac1 is detected by western blotting.
动物实验	Transient cerebral ischemia and reperfusion is prepared by BCCAO, as BCCAO is considered an ideal model to study transient cerebral ischemia and reperfusion injury-mediated inflammatory response. Mice are randomLy divided into the Sham, Model, Astragaloside IV (10 mg/kg) and Astragaloside IV (20 mg/kg) treatment groups. The Astragaloside IV treatment groups are intragastrically administered 7 days before the surgery and terminated on the day of sacrifice. On the day of the surgery, Astragaloside IV is administrated 2 h prior to ischemia. The Sham-operated and Model groups are treated with distilled water. After the mice are anesthetized with an intraperitoneal injection of chloral hydrate (350 mg/kg), the bilateral common carotid arteries are exposed and carefully separated with a small ventral neck incision and occluded twice (20 min each) with ligated surgical silk as described previously with minor modifications. There is a 10 min reperfusion period between the two occlusion periods (ischemia 20 min ? reperfusion 10 min ? ischemia 20 min). Sham-operated mice are subjected to the same surgical operation without the surgical silk ligation. Mouse body temperature is maintained at 37±0.5°C during the surgery with heating equipment until recovery from the anesthesia.
体内活性	雄性SD大鼠接受右侧大脑中动脉闭塞120分钟，口服AST（40mg/kg）。再灌注后1、3、7和14天将大鼠断头。AST可显著降低神经功能缺损评分；提高SOD和LDH活性，降低NOS活性和MDA、LD和NO含量。AST处理可下调iNOS mRNA的表达，而NGF和TrkA mRNA的表达上调。数据表明，AST在不同再灌注时间点对大鼠局灶性脑缺血具有保护作用，其机制可能与抗氧化有关，调节iNOS、NGF和TrkA mRNA的表达。
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度	DMSO : 50.00 mg/mL (78.06 mM), Sonication is recommended.
关键字	MMP-9 \| MMP-2 \| JNK \| ERK2 \| ERK1 \| Astragaloside
相关产品	Urea \| Rhamnose monohydrate \| Doxycycline (hyclate) \| Lactose \| Anethole \| Meloxicam \| Doxycycline \| Glucosamine \| Gum arabic \| Gluconate Calcium \| TBHQ \| Edaravone

黄芪总皂苷|TargetMol

上海陶术生物科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起，为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设筛选事业部，化学事业部，生物事业部和新材料部。从虚拟筛选到实体化合物分子供应；从商业化产品销售到个性化定制合成；从对明确靶点的分子筛选到对明确分子的多靶点筛选，从高通量筛选到化学结构优化，我们都可以满足您的科研用品及技术服务的需求。经过在中国市场五年的精心耕耘，我们已成为筛选化合物领域优秀的供应商，为超过五百家学校和各类企业提供了品质卓越的小分子化合物和药物筛

成立日期	(14年)
注册资本	566.2651万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,试剂,定制,服务
主营行业	化学试剂,生物活性小分子