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IGLC2抗体

Mouse Monoclonal IGLC2 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期:2025-05-10

湖北瑞和宁生物科技有限公司

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联系人:周***
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产品详情:

中文名称:
IGLC2抗体
英文名称:
Mouse Monoclonal IGLC2 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 945 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Mouse
偶联物:
靶点:
IGLC2

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200 - 1/1000 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

产品详情

AliasesIGLC
Entrez GeneID3538
clone5E12B9
WB Predicted band size11.3kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human IGLC2 (AA: 1-106) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

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       Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    


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       Immunohistochemical analysis of paraffin-embedded human colon tissues using IGLC2 mouse mAb with DAB staining.    


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       Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using IGLC2 mouse mAb with DAB staining.    


           

参考文献

以下是关于IGLC2抗体的虚构示例参考文献(实际文献需通过学术数据库检索):

1. **《IGLC2作为多发性骨髓瘤诊断标志物的研究》**

- 作者:Smith A, et al.

- 摘要:探讨IGLC2抗体在检测多发性骨髓瘤患者血清异常轻链表达中的特异性,验证其作为潜在生物标志物的临床价值。

2. **《免疫球蛋白轻链基因重组中IGLC2的功能分析》**

- 作者:Li Y, et al.

- 摘要:通过IGLC2抗体标记技术,揭示IGLC2在B细胞发育过程中轻链可变区重组的作用及其调控机制。

3. **《基于单细胞测序的IGLC2抗体筛选与优化》**

- 作者:Wang X, et al.

- 摘要:报道一种新型IGLC2单克隆抗体的开发流程,评估其在流式细胞术和免疫组化中的应用效能。

4. **《自身免疫疾病中IGLC2异常表达的免疫学研究》**

- 作者:Garcia R, et al.

- 摘要:利用IGLC2抗体检测系统性红斑狼疮患者外周血B细胞,发现IGLC2过度表达与疾病活动性的相关性。

**注意**:以上为模拟示例,实际文献需通过PubMed、Google Scholar等平台检索关键词“IGLC2 antibody”或“immunoglobulin lambda constant 2”获取。

       

背景信息

The IGLC2 antibody targets the immunoglobulin lambda constant 2 (IGLC2) protein, a component of the lambda light chain in immunoglobulins (antibodies). Immunoglobulins consist of two heavy chains and two light chains (kappa or lambda), with lambda chains encoded by gene clusters including IGLC2. This protein contributes to the constant region of antibodies, influencing their structural stability and effector functions, such as complement activation and receptor binding.

IGLC2 antibodies are primarily used in research to study B-cell development, antibody diversity, and pathologies involving lambda light chains, such as B-cell malignancies (e.g., multiple myeloma) or autoimmune disorders. They help detect lambda chain expression in tissues or serum, aiding in diagnostics and subtyping of monoclonal gammopathies.

Commercial IGLC2 antibodies are typically monoclonal or polyclonal, validated for techniques like immunohistochemistry, flow cytometry, or Western blot. Challenges include cross-reactivity with homologous lambda chain isoforms (e.g., IGLC1. IGLC3), necessitating careful validation. Recent studies also explore IGLC2's role in immune microenvironment regulation, highlighting its potential as a therapeutic target or biomarker. Overall, IGLC2 antibodies are vital tools for understanding humoral immunity and related diseases.

       
IGLC2抗体;IGLC2;IGLC2 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

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