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  • SHTN1抗体—艾普蒂
  • SHTN1抗体—艾普蒂
  • SHTN1抗体—艾普蒂

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SHTN1抗体—艾普蒂 新品

Rabbit Polyclonal SHTN1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-18

上海切尔齐生物科技有限公司

非会员
联系人:周***
电话:027***
手机:180***
邮箱:rui***

产品详情:

中文名称:
SHTN1抗体
英文名称:
Rabbit Polyclonal SHTN1 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 3275 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
SHTN1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesKIAA1598; shootin-1
WB Predicted band size72 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human SHTN1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue lysate, Primary antibody: P06824(SHTN1 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P06824(SHTN1 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

参考文献

以下是关于SHTN1抗体的3篇参考文献及其摘要概括(注意:SHTN1相关研究较少,以下为模拟示例,实际文献需通过学术数据库核实):

1. **文献名称**:*SHTN1 regulates synaptic plasticity through actin cytoskeleton remodeling*

**作者**:Chen L, et al.

**摘要**:本研究通过开发特异性SHTN1抗体,揭示了SHTN1蛋白在中枢神经系统突触中的定位,证明其通过调控肌动蛋白动态影响突触可塑性,为神经退行性疾病机制提供了新见解。

2. **文献名称**:*Development of a monoclonal antibody targeting SHTN1 for immunohistochemical analysis*

**作者**:Wang Y, et al.

**摘要**:报道了一种高特异性小鼠源单克隆SHTN1抗体的制备与验证,证明其在组织切片中检测SHTN1表达的可靠性,并应用于乳腺癌组织中SHTN1蛋白异常表达的临床病理分析。

3. **文献名称**:*SHTN1 knockout mice exhibit impaired learning and memory: Antibody-based validation*

**作者**:Tanaka K, et al.

**摘要**:利用SHTN1抗体验证基因敲除小鼠模型,发现SHTN1缺失导致海马区神经元树突棘密度降低,并伴随空间记忆缺陷,提示其在认知功能中的关键作用。

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**注意**:SHTN1并非广泛研究的蛋白,上述文献为假设性示例。建议通过PubMed或Google Scholar搜索最新文献(如尝试关键词"SHTN1 AND antibody"或相关功能描述)。若目标蛋白名称有误(如SHANK1/SHANK3等),需修正后重新检索。

       

背景信息

The SHTN1 antibody is a research tool developed to target the SHTN1 protein, a less-characterized molecule implicated in neuronal and synaptic functions. While its exact biological role remains under investigation, preliminary studies suggest SHTN1 may participate in cytoskeletal organization or synaptic vesicle trafficking, potentially influencing neurotransmission and neural plasticity. The antibody was generated using immunogens derived from conserved regions of the SHTN1 protein sequence, often in model organisms like mice or rabbits, yielding either monoclonal or polyclonal variants. It has been validated for applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to map SHTN1 expression patterns in brain tissues or cultured neurons. Interest in SHTN1 stems from its hypothesized link to neurodevelopmental disorders and neurodegenerative diseases, though mechanistic insights are scarce. Current research focuses on clarifying its interaction partners, subcellular localization, and potential dysregulation in disease models. However, limited commercial availability and the absence of standardized validation protocols pose challenges for reproducibility. Ongoing efforts aim to establish SHTN1's functional relevance, leveraging this antibody as a critical reagent to bridge gaps in understanding its role in neural physiology and pathology.
       
SHTN1抗体;SHTN1;SHTN1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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