COX7B2抗体—艾普蒂

+ +

•  

   

     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P07021(COX7B2 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07021(COX7B2 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The COX7B2 (Cytochrome c oxidase subunit 7B2) antibody is a tool used to detect and study the COX7B2 protein, a component of the mitochondrial respiratory chain complex IV (cytochrome c oxidase). This complex is essential for cellular energy production, as it catalyzes the final step in the electron transport chain, transferring electrons to oxygen to form water while driving ATP synthesis. COX7B2 is a nuclear-encoded subunit that contributes to the assembly and stability of complex IV, though its specific functional role remains less characterized compared to other subunits.

COX7B2 antibodies are typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. These antibodies enable researchers to investigate COX7B2 expression, localization, and abundance in tissues or cell lines using techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Dysregulation of COX7B2 has been implicated in mitochondrial disorders, metabolic syndromes, and certain cancers, making its study relevant for understanding disease mechanisms. Validated antibodies often undergo specificity checks via knockout controls or siRNA knockdown. Research utilizing COX7B2 antibodies contributes to elucidating mitochondrial dysfunction pathways and potential therapeutic targets.