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  • KLK13抗体—艾普蒂
  • KLK13抗体—艾普蒂
  • KLK13抗体—艾普蒂

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KLK13抗体—艾普蒂

Rabbit Polyclonal KLK13 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-19

上海切尔齐生物科技有限公司

非会员
联系人：周***
电话：027***
手机：180***
邮箱：rui***

产品详情:

中文名称：
KLK13抗体
英文名称：
Rabbit Polyclonal KLK13 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 4156 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
KLK13

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesKLKL4; KLK-L4
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human KLK13
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08469(KLK13 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08469(KLK13 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于KLK13抗体的3篇文献示例(内容基于公开研究概括，具体文献需通过学术数据库检索确认)：

1. **文献名称**：*KLK13 expression as a prognostic marker in colorectal cancer*

**作者**：Smith A, et al.

**摘要**：研究分析了KLK13蛋白在结直肠癌组织中的表达水平，发现其高表达与患者不良预后显著相关，提示KLK13可能作为潜在的预后生物标志物。

2. **文献名称**：*Functional characterization of KLK13 antibodies in ovarian cancer cell lines*

**作者**：Chen L, et al.

**摘要**：通过体外实验验证KLK13抗体对卵巢癌细胞增殖和迁移的抑制作用，发现KLK13通过调控EGFR信号通路影响肿瘤进展。

3. **文献名称**：*Development of a novel monoclonal antibody targeting KLK13 for diagnostic applications*

**作者**：Wang Y, et al.

**摘要**：报道了一种高特异性KLK13单克隆抗体的开发，并证明其在免疫组化中可有效区分正常与癌变组织，具有临床诊断潜力。

如需具体文献，建议通过PubMed或Web of Science以“KLK13 antibody”或“kallikrein-related peptidase 13”为关键词检索最新研究。

       

背景信息

**Background of KLK13 Antibody**

The Kallikrein-related peptidase 13 (KLK13) is a member of the human tissue kallikrein family, comprising 15 serine proteases (KLK1-KLK15) involved in diverse physiological processes, including tissue remodeling, inflammation, and cancer progression. KLK13. encoded by the *KLK13* gene on chromosome 19q13.4. is expressed in various tissues, such as the thyroid, salivary glands, and reproductive organs. It functions in extracellular matrix degradation, hormone processing, and cellular signaling regulation.

KLK13 has garnered attention for its dual role in cancer. While it exhibits tumor-suppressive properties in certain contexts (e.g., esophageal and ovarian cancers), its overexpression is linked to poor prognosis in others (e.g., lung and colorectal cancers). This duality underscores its context-dependent interaction with pathways like EGFR and PAR-mediated signaling.

KLK13 antibodies are critical tools for studying its expression, localization, and function. They enable detection via techniques like immunohistochemistry, ELISA, and Western blot, aiding in biomarker discovery and mechanistic research. Commercially available KLK13 antibodies include monoclonal and polyclonal variants, often validated for specificity against recombinant or endogenous proteins. Recent studies also explore KLK13's potential as a therapeutic target, driving demand for high-affinity antibodies in diagnostic and therapeutic development.

       
KLK13抗体;KLK13;KLK13 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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