CEBPZ抗体;CEBPZ Antibody—艾普蒂

+ +

•  

   

     Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela, 293T and K562 cell lysates, Primary antibody: P13023(CEBPZ Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P13023(CEBPZ Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13023(CEBPZ Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The CEBPZ (CCAAT enhancer-binding protein zeta) antibody is a tool used to detect and study the CEBPZ protein, a transcription factor implicated in regulating gene expression. CEBPZ belongs to the C/EBP family of proteins, which play critical roles in cellular processes like proliferation, differentiation, and apoptosis. Unlike other C/EBP members, CEBPZ is less characterized but has been linked to RNA processing, chromatin remodeling, and ribosome biogenesis. It interacts with RNA polymerase II and components of the transcription machinery, suggesting involvement in transcriptional elongation or mRNA maturation.

Antibodies targeting CEBPZ enable researchers to investigate its expression, localization, and function via techniques like Western blotting, immunofluorescence, or chromatin immunoprecipitation (ChIP). These antibodies are typically validated for specificity using knockdown/knockout controls or peptide-blocking assays. CEBPZ is expressed ubiquitously, with studies highlighting its potential role in cancer, neurodevelopment, and stress responses. Dysregulation of CEBPZ has been observed in certain malignancies, though its precise mechanistic contributions remain under exploration. The antibody thus serves as a key reagent for unraveling CEBPZ's biological significance in health and disease.