RPS9抗体;RPS9 Antibody—艾普蒂

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     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: LOVO, HUVEC, HepG2, 293T cell lysates, Primary antibody: P13773(RPS9 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P13773(RPS9 Antibody) at dilution 1/50. (Original magnification: ×200)    

  
  

The RPS9 antibody is a tool used to detect Ribosomal Protein S9 (RPS9), a component of the 40S ribosomal subunit involved in protein synthesis. RPS9. encoded by the RPS9 gene, is a conserved, ubiquitously expressed protein with a molecular weight of approximately 22 kDa. Structurally, it contributes to ribosome assembly and stability, playing a critical role in mRNA binding and translation fidelity. Beyond its canonical role in ribosome biogenesis, RPS9 has been implicated in non-ribosomal functions, including cell proliferation, apoptosis, and stress response pathways. Dysregulation of RPS9 expression is linked to various diseases, such as cancer (e.g., colorectal, breast) and Diamond-Blackfan anemia, a rare genetic disorder caused by ribosomal protein mutations.

RPS9 antibodies are widely used in research to study protein localization, expression levels, and interactions via techniques like Western blotting, immunohistochemistry, and immunofluorescence. They are also employed to explore ribosomal dysfunction mechanisms and validate disease models. Commercially available RPS9 antibodies are typically monoclonal or polyclonal, often validated for specificity using knockout controls or siRNA-mediated silencing. Due to potential cross-reactivity with homologous proteins, validation in specific experimental systems is essential. These antibodies serve as vital tools for unraveling ribosome-related cellular processes and their pathological implications.