CHX10抗体;CHX10 Antibody—艾普蒂

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

The CHX10 antibody is a crucial tool in neuroscience and developmental biology research, targeting the CHX10 protein (also known as VSX2), a homeodomain transcription factor encoded by the *VSX2* gene. CHX10 plays a pivotal role in retinal development, particularly in the differentiation and maintenance of bipolar cells within the retina, as well as in spinal cord interneuron specification. Its expression is tightly regulated during embryogenesis, and mutations in *VSX2* are linked to ocular disorders such as microphthalmia (abnormally small eyes) and congenital blindness.

The CHX10 antibody is widely used to identify and study CHX10-expressing cells in tissue sections, aiding investigations into retinal circuitry, developmental defects, and regenerative therapies. Researchers employ it in techniques like immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting to visualize protein localization and expression levels. It has also become valuable in stem cell research, where tracking CHX10 helps assess the differentiation of retinal progenitor cells in vitro.

Beyond basic science, this antibody supports disease modeling and drug discovery for vision-related pathologies. Its specificity and reliability make it a cornerstone in understanding how CHX10 contributes to visual system development and dysfunction, offering insights into potential therapeutic strategies for retinal degenerative diseases.