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  • (Elgemtumab)Biosimilar Reference Antibody-GS40214
  • (Elgemtumab)Biosimilar Reference Antibody-GS40214
  • (Elgemtumab)Biosimilar Reference Antibody-GS40214

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(Elgemtumab)Biosimilar Reference Antibody-GS40214

Elgemtumab
300 100μg 起订
湖北 更新日期:2026-03-13

武汉迈思生物科技有限公司

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联系人:市场
电话:027-65523427拨打
手机:18007167883 拨打
邮箱:Service@mabnus.com

产品详情:

英文名称:
Elgemtumab
CAS号:
1512559-37-3
品牌:
Mabnus
产地:
武汉
保存条件:
store at -20°C or -80°C. Avoid repeated freeze.
纯度规格:
>95% by SDS-PAGE
重组:
应用:
ELISA;FC;Functional Assays;IF
种属反应性:
Human
宿主:
Genetically human
偶联物:
靶点:
ERBB3/HER3
免疫原:
ERBB3/HER3
亚型:
IgG1 - kappa
验证方法:
(Elgemtumab)Biosimilar Reference Antibody(GS40214) on SDS-PAGE under non-reducing (NR) and reducing (R) condition.

货号:GS40214

Elgemtumab (development code LJM716) is an investigational, fully human immunoglobulin G (IgG) monoclonal antibody developed as a targeted therapy for cancers driven by HER3 signaling. It functions as a potent and specific HER3 antagonist. Its mechanism of action is to bind with high affinity to the extracellular domain of HER3, thereby effectively blocking both ligand-dependent and ligand-independent HER3 signaling pathways. This dual blockade prevents the activation and subsequent dimerization of HER3 with other ErbB family receptors (like HER2 or EGFR), a critical step for downstream oncogenic signaling that promotes tumor cell survival, proliferation, and resistance to therapy.


Elgemtumab;

公司简介

武汉迈思生物科技有限公司立足于解决行业内功能活性蛋白表达及高亲和力、高灵敏度抗体开发难的痛点,依托自建的两大核心技术平台:哺乳动物细胞蛋白表达平台和单个B细胞抗体开发平台,竭诚为广大科研机构、高等院校、IVD企业、医药企业等提供一站式蛋白表达及抗体开发相关产品和技术服务。

成立日期 (5年)
注册资本 壹佰伍拾万圆人民币
员工人数 10-50人
年营业额 ¥ 1000万-5000万
经营模式 工厂,试剂,定制,服务
主营行业 抗体,蛋白组学

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