人STEAP2蛋白, Flag Tag

Human STEAP2 Full Length Protein, Flag Tag (Nanodisc-pro)

分子别名（Synonym）

STEAP2

表达区间及表达系统（Source）

Human STEAP2 Full Length Protein, Flag Tag (ST2-H55C3) is expressed from Baculovirus-Insect cells. It contains AA Glu 2 - Met 490 (Accession # Q8NFT2-1).

Predicted N-terminus: Met

蛋白结构（Molecular Characterization）

This protein carries a flag tag at the C-terminus.

The protein has a calculated MW of 57.7 kDa.

Nanodiscs are a new class of model membranes that are being used to solubilize and study a range of integral membrane proteins and membrane-associated proteins. The Nanodisc bilayer is bounded by an amphipathic scaffold coat that confers enhanced stability and a narrow particle size distribution.

The nanodisc-pro is directly extracted from cell membrane in a water-soluble form using an amphipathic scaffold followed by affinity chromatography, and thus, it conserves a patch of native membrane around them.

纯度（Purity）

>90% as determined by SDS-PAGE.

制剂（Formulation）

Supplied as 0.2 μm filtered solution in 20 mM HEPES, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

运输（Shipping）

This product is supplied and shipped with dry ice, please inquire the shipping cost.

存储（Storage）

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;

-70°C for 3 months under sterile conditions.

背景介绍

该基因是STEAP家族的一员，编码一种多次跨膜蛋白，定位于高尔基体、质膜以及细胞质中的囊泡管状结构。在小鼠中，一种高度相似的蛋白质同时具有铁还原酶和铜还原酶活性，并在体外刺激细胞对铁和铜的吸收。该人类基因转录表达的增加与前列腺癌的进展相关。目前，已鉴定出编码不同异构体的选择性转录剪接变体。