2,5-Dibromopyridine:Reactivity,Uses and Hazard

Pyridine and its derivatives is distributed in nature widely. Many plant constituents are as all contained pyridine ring compound in the structure of alkaloid etc. 2,5-Dibromopyridine is the important intermediate of organic synthesis, is mainly used in medicine intermediate, organic synthesis, organic solvent, also can be applicable to the aspects such as dye production, pesticide producing and spices.

Reactivity

2,5-Dibromopyridine is chemically stable under standard ambient conditions (room temperature) . It reacts with strong oxidizing agents.

Uses

2,5-Dibromopyridine can be used as a coupling agent in palladium-catalyzed cross-coupling reactions. It is used on the surface of metal particles to increase the efficiency of the reaction, and has been shown to react with substrates such as sodium hydroxide solution, sodium carbonate, halides and hydroxides. 2,5-Dibromopyridine also reacts with benzoate to form a palladium complex. 2,5-Dibromopyridine can be used as an oxidant or reductant depending on the type of reaction it is being used in. It has redox potentials at -0.6 volts for oxidation and +0.6 volts for reduction.

Hazard

2,5-Dibromopyridine causes skin irritation and serious eye irritation. It may cause respiratory irritation.

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