Are α-ketoglutarate (AKG) and 2-Ketoglutaric acid (2-KG) the same substance?

α-Ketoglutarate (AKG) and 2-Ketoglutaric acid (2-KG) are the same substance, just with different names. They are completely identical in chemical structure, CAS number, and practical applications, and are often referred to as 2-oxoglutarate. It is a key metabolic intermediate in the tricarboxylic acid cycle, belonging to the endogenous organic acids in the human body. It participates in both energy and nitrogen metabolism and is frequently used as a core ingredient in sports nutrition, dietary supplements, biomedicine, and feed additives. Because it supports bodily recovery and improves metabolic status, it is widely used in health maintenance and professional sports settings.

You may like