Can Ascorbyl glucoside be used for skin whitening?

Yes. Ascorbyl glucoside (AA2G) is a whitening agent approved in Japan. It exerts a depigmenting effect on UVB-induced hyperpigmentation either as a tyrosinase inhibitor or by converting to free ascorbic acid via epidermal glucosidase. AA2G is essentially a water-soluble, stable vitamin C derivative with antioxidant properties, utilised in numerous cosmetic whitening formulations. It is typically employed at concentrations of 2-5% to brighten dull skin and diminish the appearance of hyperpigmentation. Furthermore, the ascorbyl glucoside-arginine complex (AGAC) demonstrably improves the pigmentation levels of solar lentigines (SLs) without inducing any depigmentation or skin issues.

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