How is 4-tert-Butoxystyrene synthesized?

4-tert-Butoxystyrene can be synthesized via a Grignard reaction. Typically, a Grignard reagent, such as phenylmagnesium bromide, is prepared by reacting magnesium with bromobenzene in anhydrous ether or tetrahydrofuran (THF). This Grignard reagent is then reacted with tert-butyl acetate. The resulting intermediate undergoes hydrolysis to yield 4-tert-butoxystyrene. The product is purified through standard techniques such as distillation to obtain the desired compound.

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