In what reactions is X-PHOS primarily used as a ligand?

X-PHOS is a white to pale yellow crystalline solid and phosphine ligand, It is also an efficient ligand for several commonly used C–C bond-forming cross-coupling reactions, including the Negishi, Suzuki, and the copper-free Sonogashira coupling reactions. It is especially efficient and general when employed as a (2-aminobiphenyl)-cyclometalated palladium mesylate precatalyst complex (Buchwald's third generation precatalyst system).

You may like